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Gene Kwan, MD

Lecturer on Global Health and Social Medicine, Harvard Medical School
Assistant Professor of Medicine, Boston University School of Medicine
Associate Director of Cardiovascular Research and Training, Partners In Health

I am a cardiologist and global health researcher developing expertise in the intersection between these two fields. My primary professional goal is to push the frontier of global cardiovascular disease epidemiology and health service delivery (implementation) research through the development, implementation, evaluation, improvement and dissemination of integrated chronic care programs targeted to overcome specific barriers in rural low- and middle-income countries (LMIC). 

My research stems from experience in the field in rural Rwanda and Haiti since 2008 in collaboration with local Ministries of Health and the non-governmental organizations Partners In Health and Zanmi Lasante. I have developed and implemented care models using the strategy of task-shifting: training in-country nurses and generalist physicians in simplified protocols to aid in specialty care for the diagnosis and management of non-communicable diseases (NCD) including hypertension, diabetes, heart failure, stroke, and respiratory disease. My research has helped determine that heart failure in rural Rwanda and Haiti is generally from endemic causes (as opposed to coronary heart disease) and a leading cause of hospitalization. In addition, we demonstrated that nurse-directed management improves control of blood pressure for patients with hypertension and improves symptoms for those with heart failure. I also study the prevalence of poverty among patients with NCDs and develop approaches to overcome poverty-related barriers. My long-term goal is to develop and utilize evidence-based approaches for the understanding of cardiovascular disease in LMICs and influence programmatic development, implementation and policy.

I have active academic collaborations with projects in Haiti, Rwanda, Malawi, Liberia, and India. I am one of the principal authors of the implementation guide and clinician handbook The Partners In Health Guide to Chronic Care Integration for Endemic Non-Communicable Diseases. I have presented my work at several American Heart Association conferences including the Annual Scientific Sessions, Epidemiology, Nutrition, Prevention and Metabolism, and Quality and Clinical Outcomes Research sessions. I have also been an invited speaker both nationally and in Haiti and Rwanda. I continue to serve as an Advisor for Non-Communicable Diseases at Partners In Health in Boston, Haiti and Rwanda.

Cost of integrated chronic care for severe non-communicable diseases at district hospitals in rural Rwanda.
Authors: Authors: Eberly LA, Rusangwa C, Ng'ang'a L, Neal CC, Mukundiyukuri JP, Mpanusingo E, Mungunga JC, Habineza H, Anderson T, Ngoga G, Dusabeyezu S, Kwan G, Bavuma C, Rusingiza E, Mutabazi F, Mucumbitsi J, Gahamanyi C, Mutumbira C, Park PH, Mpunga T, Bukhman G.
BMJ Glob Health
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Understanding the Etiology of Heart Failure Among the Rural Poor in Sub-Saharan Africa: A 10-Year Experience From District Hospitals in Rwanda.
Authors: Authors: Eberly LA, Rusingiza E, Park PH, Ngoga G, Dusabeyezu S, Mutabazi F, Harerimana E, Mucumbitsi J, Nyembo PF, Borg R, Gahamanyi C, Mutumbira C, Ntaganda E, Rusangwa C, Kwan GF, Bukhman G.
J Card Fail
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Nurse-Driven Echocardiography and Management of Heart Failure at District Hospitals in Rural Rwanda.
Authors: Authors: Eberly LA, Rusingiza E, Park PH, Ngoga G, Dusabeyezu S, Mutabazi F, Harerimana E, Mucumbitsi J, Nyembo PF, Borg R, Gahamanyi C, Mutumbira C, Ntaganda E, Rusangwa C, Kwan GF, Bukhman G.
Circ Cardiovasc Qual Outcomes
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Outcomes for patients with rheumatic heart disease after cardiac surgery followed at rural district hospitals in Rwanda.
Authors: Authors: Rusingiza EK, El-Khatib Z, Hedt-Gauthier B, Ngoga G, Dusabeyezu S, Tapela N, Mutumbira C, Mutabazi F, Harelimana E, Mucumbitsi J, Kwan GF, Bukhman G.
Heart
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Racial Differences in Hospital Death for Atrial Fibrillation: The National Inpatient Sample 2001-2012.
Authors: Authors: Kwan GF, Enserro DM, Benjamin EJ, Walkey AJ, Wiener RS, Magnani JW.
Proclins Cardiol
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Global, Regional, and National Burden of Cardiovascular Diseases for 10 Causes, 1990 to 2015.
Authors: Authors: Roth GA, Johnson C, Abajobir A, Abd-Allah F, Abera SF, Abyu G, Ahmed M, Aksut B, Alam T, Alam K, Alla F, Alvis-Guzman N, Amrock S, Ansari H, Ärnlöv J, Asayesh H, Atey TM, Avila-Burgos L, Awasthi A, Banerjee A, Barac A, Bärnighausen T, Barregard L, Bedi N, Belay Ketema E, Bennett D, Berhe G, Bhutta Z, Bitew S, Carapetis J, Carrero JJ, Malta DC, Castañeda-Orjuela CA, Castillo-Rivas J, Catalá-López F, Choi JY, Christensen H, Cirillo M, Cooper L, Criqui M, Cundiff D, Damasceno A, Dandona L, Dandona R, Davletov K, Dharmaratne S, Dorairaj P, Dubey M, Ehrenkranz R, El Sayed Zaki M, Faraon EJA, Esteghamati A, Farid T, Farvid M, Feigin V, Ding EL, Fowkes G, Gebrehiwot T, Gillum R, Gold A, Gona P, Gupta R, Habtewold TD, Hafezi-Nejad N, Hailu T, Hailu GB, Hankey G, Hassen HY, Abate KH, Havmoeller R, Hay SI, Horino M, Hotez PJ, Jacobsen K, James S, Javanbakht M, Jeemon P, John D, Jonas J, Kalkonde Y, Karimkhani C, Kasaeian A, Khader Y, Khan A, Khang YH, Khera S, Khoja AT, Khubchandani J, Kim D, Kolte D, Kosen S, Krohn KJ, Kumar GA, Kwan GF, Lal DK, Larsson A, Linn S, Lopez A, Lotufo PA, El Razek HMA, Malekzadeh R, Mazidi M, Meier T, Meles KG, Mensah G, Meretoja A, Mezgebe H, Miller T, Mirrakhimov E, Mohammed S, Moran AE, Musa KI, Narula J, Neal B, Ngalesoni F, Nguyen G, Obermeyer CM, Owolabi M, Patton G, Pedro J, Qato D, Qorbani M, Rahimi K, Rai RK, Rawaf S, Ribeiro A, Safiri S, Salomon JA, Santos I, Santric Milicevic M, Sartorius B, Schutte A, Sepanlou S, Shaikh MA, Shin MJ, Shishehbor M, Shore H, Silva DAS, Sobngwi E, Stranges S, Swaminathan S, Tabarés-Seisdedos R, Tadele Atnafu N, Tesfay F, Thakur JS, Thrift A, Topor-Madry R, Truelsen T, Tyrovolas S, Ukwaja KN, Uthman O, Vasankari T, Vlassov V, Vollset SE, Wakayo T, Watkins D, Weintraub R, Werdecker A, Westerman R, Wiysonge CS, Wolfe C, Workicho A, Xu G, Yano Y, Yip P, Yonemoto N, Younis M, Yu C, Vos T, Naghavi M, Murray C.
J Am Coll Cardiol
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Rheumatic Heart Disease: The Unfinished Global Agenda.
Authors: Authors: Nulu S, Bukhman G, Kwan GF.
Cardiol Clin
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Cardiovascular Complications of HIV in Endemic Countries.
Authors: Authors: Feinstein MJ, Bogorodskaya M, Bloomfield GS, Vedanthan R, Siedner MJ, Kwan GF, Longenecker CT.
Curr Cardiol Rep
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Response by Wirtz et al to Letter Regarding Article, "Access to Medications for Cardiovascular Diseases in Low- and Middle-Income Countries".
Authors: Authors: Wirtz VJ, Kaplan WA, Kwan GF, Laing RO.
Circulation
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Global epidemiology of atrial fibrillation.
Authors: Authors: Rahman F, Kwan GF, Benjamin EJ.
Nat Rev Cardiol
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