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Meredith Brooks, PhD
Instructor in Global Health and Social Medicine, Harvard Medical School

Meredith Brooks, PhD, MPH is an Instructor in Global Health and Social Medicine at Harvard Medical School. She has been in the Department since 2011 working on a wide variety of tuberculosis (TB) research projects, including international clinical trials to evaluate the safety and efficacy of TB treatments. Dr. Brooks obtained her PhD in Population Health in 2017, and previously an MPH in 2013, from Northeastern University. Her dissertation work was dedicated to applying more robust methodologies to reduce bias in the analyses of observational cohort data-- specifically, TB treatment cohort analyses. After graduating she completed a two-year postdoctoral fellowship under Professor Mercedes Becerra, focusing on TB epidemiology.

Dr. Brooks’ research interests include identifying effective implementation strategies to detect exposed individuals, with a particular interest in children, at high-risk of developing TB disease. Aims of her current projects include:

  1. to characterize the geospatial heterogeneity of TB, drug resistance, and associated individual- and neighborhood-level risk factors to inform targeted screening interventions and resource allocation;
  2. to identify risk factors for TB infection, TB disease progression, and poor treatment outcomes in children and adolescents, for whom guidelines are deficient; and
  3. to refine screening algorithms to better categorize children with TB disease and infection.

Dr. Brooks is an epidemiologist working with the Zero TB Initiative (https://www.zerotbinitiative.org) on their quest to utilize proven, comprehensive, community-based approaches to move high-burden areas closer towards TB elimination. She also works with the START Coalition (https://start-coalition.org) in designing a series of pilot programs, including seroprevalence surveys, across the US to create Covid-safe communities.

Tuberculosis clinical presentation and treatment outcomes in pregnancy: a prospective cohort study.
Authors: Authors: van de Water BJ, Brooks MB, Huang CC, Trevisi L, Lecca L, Contreras C, Galea J, Calderon R, Yataco R, Murray M, Becerra MC.
BMC Infect Dis
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Concordance of drug resistance profiles between persons with drug-resistant tuberculosis and their household contacts: a systematic review and meta-analysis.
Authors: Authors: Chiang SS, Brooks MB, Jenkins HE, Rubenstein D, Seddon JA, van de Water BJ, Lindeborg MM, Becerra MC, Yuen CM.
Clin Infect Dis
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Comparison of censoring assumptions to reduce bias in tuberculosis treatment cohort analyses.
Authors: Authors: Brooks MB, Mitnick CD, Manjourides J.
PLoS One
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Reply to te Brake et al.: Conflicting Findings on an Intermediate Dose of Rifampicin for Pulmonary Tuberculosis.
Authors: Authors: Velásquez GE, Brooks MB, Coit JM, Sánchez Garavito E, Calderón RI, Jiménez J, Tintaya K, Peloquin CA, Osso E, Lecca L, Davies GR, Mitnick CD.
Am J Respir Crit Care Med
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Pharmacokinetics of Levofloxacin in Children Treated for Exposure to Drug-Resistant Tuberculosis.
Authors: Authors: Malik AA, Brooks MB, Siddiqui S, Fuad J, Peloquin CA, Amanullah F, Jaswal M, Becerra MC, Hussain H, Yuen CM.
Antimicrob Agents Chemother
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Barriers and facilitators to early access of bedaquiline and delamanid for MDR-TB: a mixed-methods study.
Authors: Authors: Rodriguez CA, Brooks MB, Guglielmetti L, Hewison C, Jachym MF, Lessem E, Varaine F, Mitnick CD.
Public Health Action
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Establishing a relationship between the effect of caffeine and duration of endurance athletic time trial events: A systematic review and meta-analysis.
Authors: Authors: Shen JG, Brooks MB, Cincotta J, Manjourides JD.
J Sci Med Sport
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Process measure of FAST tuberculosis infection control demonstrates delay in likely effective treatment.
Authors: Authors: Le H, Nguyen N, Tran P, Hoa N, Hung N, Moran A, Mossawi HJA, Kak N, Ahmedov S, Brooks MB, Nardell EA, Tierney DB.
Int J Tuberc Lung Dis
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Risk factors for unsuccessful tuberculosis treatment outcomes in children.
Authors: Authors: Hamid M, Brooks MB, Madhani F, Ali H, Naseer MJ, Becerra M, Amanullah F.
PLoS One
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Evaluation of GenoType MTBDRplus for the detection of drug-resistant Mycobacterium tuberculosis on isolates from Karachi, Pakistan.
Authors: Authors: Siddiqui S, Brooks MB, Malik AA, Fuad J, Nazish A, Bano S, Becerra MC, Hussain H.
PLoS One
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