Molly Franke

Molly Forrest Franke, SD

Assistant Professor of Global Health and Social Medicine

Phone:

(617) 432-5224

molly_franke@hms.harvard.edu

Tabs

Research

Dr. Franke applies robust epidemiologic methods to intractable conditions disproportionately affecting poor people in diverse settings around the world. Her research spans infectious diseases (tuberculosis [TB], HIV, cholera) and chronic diseases (diabetes, hypertension, depression) and focuses on the identification of effective care delivery strategies for patients with these conditions.

Research Interests

Community-based accompaniment interventions
Pediatric tuberculosis
Interventions to improve outcomes for adolescents living with HIV
Cholera prevention and transmission elimination
Application of causal inference methods to observational data

Current Projects

Alternative specimen types for pediatric tuberculosis diagnosis
Diagnostic and treatment delays in pediatric tuberculosis
Effectiveness and safety of bedaquiline and delamanid among patients with multidrug-resistant TB (endTB project)
Targeted elimination of cholera transmission in rural Haiti
Adolescent-friendly rap videos to improve health literacy among HIV-positive youth in urban Peru

Biography

Dr. Franke earned a BA degree in sociology and Spanish from Colby College. She then went to work as a research analyst for the Massachusetts Department of Public Health Epidemiology & Immunization Surveillance Program and as a research assistant with Partners In Health in Lima, Peru. While pursuing her doctoral degree in epidemiology at Harvard T.H. Chan School of Public Health, she conducted field research at Partners In Health sites in Peru and Rwanda. She joined the Department of Global Health and Social Medicine in 2010. In addition to pursuing independent research, Dr. Franke is a member of the Global Health Research Core. In this role, she serves as lead epidemiologist and analyst for multiple research projects of the Global Health Delivery Partnership, including projects based in Haiti, Papua New Guinea, and Mexico.

Publications

Automated TruTip nucleic acid extraction and purification from raw sputum.

Molly Forrest Franke, SD, Megan Blanche Murray, DPH, MD

PloS one, July 5, 2018

Thakore N, Norville R, Franke M, Calderon R, Lecca L, Villanueva M, Murray MB, Cooney CG, Chandler DP, Holmberg RC

Link to abstract on PubMed

Genotyping Multidrug-Resistant Mycobacterium tuberculosis from Primary Sputum and Decontaminated Sediment with an Integrated Microfluidic Amplification Microarray Test.

Molly Forrest Franke, SD, Megan Blanche Murray, DPH, MD

Journal of clinical microbiology, February 22, 2018

Linger Y, Knickerbocker C, Sipes D, Golova J, Franke M, Calderon R, Lecca L, Thakore N, Holmberg R, Qu P, Kukhtin A, Murray MB, Cooney CG, Chandler DP

Link to abstract on PubMed

Barriers and facilitators to antiretroviral therapy adherence among Peruvian adolescents living with HIV: A qualitative study.

Molly Forrest Franke, SD

PloS one, February 15, 2018

Galea JT, Wong M, Muñoz M, Valle E, Leon SR, Díaz Perez D, Kolevic L, Franke M

Link to abstract on PubMed

Community health workers improve disease control and medication adherence among patients with diabetes and/or hypertension in Chiapas, Mexico: an observational stepped-wedge study.

Molly Forrest Franke, SD, Daniel Palazuelos, MD

BMJ global health, February 15, 2018

Newman PM, Franke MF, Arrieta J, Carrasco H, Elliott P, Flores H, Friedman A, Graham S, Martinez L, Palazuelos L, Savage K, Tymeson H, Palazuelos D

Link to abstract on PubMed

Vitamin E Status Is Inversely Associated with Risk of Incident Tuberculosis Disease among Household Contacts.

Molly Forrest Franke, SD, Megan Blanche Murray, DPH, MD

The Journal of nutrition, January 1, 2018

Aibana O, Franke MF, Huang CC, Galea JT, Calderon R, Zhang Z, Becerra MC, Smith ER, Contreras C, Yataco R, Lecca L, Murray MB

Link to abstract on PubMed

Community-Based Accompaniment with Supervised Antiretrovirals for HIV-Positive Adults in Peru: A Cluster-Randomized Trial.

Molly Forrest Franke, SD, Leonid Lecca, MD, MSc

AIDS and behavior, January 1, 2018

McLaughlin MM, Franke MF, Muñoz M, Nelson AK, Saldaña O, Cruz JS, Wong M, Zhang Z, Lecca L, Ticona E, Arevalo J, Sanchez E, Sebastián JL, Shin S

Link to abstract on PubMed

The Impact of a Community-Based Intervention Including a Monthly Food Ration on Food Insecurity Among HIV-Positive Adults During the First Year of Antiretroviral Therapy.

Molly Forrest Franke, SD

AIDS and behavior, January 1, 2018

Rothman J, Kayigamba F, Hills V, Gupta N, Machara F, Niyigena P, Franke MF

Link to abstract on PubMed

Laboratory evaluation of immunochromatographic rapid diagnostic tests for cholera in Haiti.

Molly Forrest Franke, SD, Louise Catherine Ivers, MB, BCh, MD, MPH, DTM&H

PloS one, November 1, 2017

Matias WR, Julceus FE, Abelard C, Mayo-Smith LM, Franke MF, Harris JB, Ivers LC

Link to abstract on PubMed

Fluoroquinolone Resistance Mutation Detection Is Equivalent to Culture-Based Drug Sensitivity Testing for Predicting Multidrug-Resistant Tuberculosis Treatment Outcome: A Retrospective Cohort Study.

Maha Reda Farhat, MD, Molly Forrest Franke, SD, Carole Diane Mitnick, Sc.D.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, October 15, 2017

Farhat MR, Jacobson KR, Franke MF, Kaur D, Murray M, Mitnick CD

Link to abstract on PubMed

Development and Validation of a Food Frequency Questionnaire to Estimate Intake among Children and Adolescents in Urban Peru.

Carly Alicia Rodriguez, Megan Blanche Murray, DPH, MD, Molly Forrest Franke, SD

Nutrients, October 14, 2017

Rodriguez CA, Smith ER, Villamor E, Zavaleta N, Respicio-Torres G, Contreras C, Perea S, Jimenez J, Tintaya K, Lecca L, Murray MB, Franke MF

Link to abstract on PubMed

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Tabs

Automated TruTip nucleic acid extraction and purification from raw sputum.

Genotyping Multidrug-Resistant Mycobacterium tuberculosis from Primary Sputum and Decontaminated Sediment with an Integrated Microfluidic Amplification Microarray Test.

Barriers and facilitators to antiretroviral therapy adherence among Peruvian adolescents living with HIV: A qualitative study.

Community health workers improve disease control and medication adherence among patients with diabetes and/or hypertension in Chiapas, Mexico: an observational stepped-wedge study.

Vitamin E Status Is Inversely Associated with Risk of Incident Tuberculosis Disease among Household Contacts.

Community-Based Accompaniment with Supervised Antiretrovirals for HIV-Positive Adults in Peru: A Cluster-Randomized Trial.

The Impact of a Community-Based Intervention Including a Monthly Food Ration on Food Insecurity Among HIV-Positive Adults During the First Year of Antiretroviral Therapy.

Laboratory evaluation of immunochromatographic rapid diagnostic tests for cholera in Haiti.

Fluoroquinolone Resistance Mutation Detection Is Equivalent to Culture-Based Drug Sensitivity Testing for Predicting Multidrug-Resistant Tuberculosis Treatment Outcome: A Retrospective Cohort Study.

Development and Validation of a Food Frequency Questionnaire to Estimate Intake among Children and Adolescents in Urban Peru.