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Alexandra Golby, MD

Professor of Neurosurgery, Harvard Medical School
Professor of Radiology, Harvard Medical School
Department of Global Health and Social Medicine Affiliate
Haley Distinguished Chair in the Neurosciences, Brigham and Women's Hospital
Senior Surgeon, Brigham and Women's Hospital
Director of Image-guided Neurosurgery, Brigham and Women's Hospital
Co-Director AMIGO, Brigham and Women's Hospital

Dr. Golby is a Neurosurgeon and Haley Distinguished Chair in the Neurosciences at Brigham and Women’s Hospital in Boston. She is Professor of Neurosurgery and Professor of Radiology at Harvard Medical School.  She is also Principal Investigator of the Golby Lab, a surgical brain mapping laboratory. Dr. Golby’s clinical focus is on brain surgery for patients with brain tumors and epilepsy, especially those lesions which are intimately associated with critical brain structures. Her translational research is focused on advanced imaging and image guidance to improve care for patients undergoing intracranial neurosurgery. She has developed numerous technologies to help guide presurgical planning and intraoperative decision-making. She works closely with scientists across disciplines including computer science, applied mathematics, MR and ultrasound physics, radiology, neuroscience, and biomedical engineering. She is very involved with mentoring young clinicians and scientists both locally and globally. Dr. Golby was recently a Fulbright Global Scholar pursuing work to foster interdisciplinary collaborations between technical experts and clinicians in host countries Rwanda and Morocco to develop innovative medical technology suited to local conditions.

Dr. Golby received her BA from Yale University and MD from Stanford University School of Medicine. She completed residency training in Neurosurgery at Brigham and Women’s Hospital.

The Golby Lab is a multidisciplinary team of investigators using advanced imaging, image analysis, and computational strategies to develop novel approaches to guide neurosurgery. Areas of interest include using functional MRI to map cortical organization and diffusion MRI to map white matter connections, intra-operative imaging, navigation and guidance, and image guided therapies for brain tumors. She is the co-director of AMIGO, the advanced multi-modality Image guided OR, an NIH-funded translational research operating suite where surgeons and interventionalists work with radiologists and technical experts to develop novel therapies to provide precise, minimally invasive, and effective treatments to patients. She leads the development of NousNav a low-cost open-source neuronavigation system for use in resource-limited settings.

Unbiased groupwise registration of white matter tractography.
Authors: Authors: O'Donnell LJ, Wells WM, Golby AJ, Westin CF.
Med Image Comput Comput Assist Interv
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Quickest detection of drug-resistant seizures: an optimal control approach.
Authors: Authors: Santaniello S, Burns SP, Golby AJ, Singer JM, Anderson WS, Sarma SV.
Epilepsy Behav
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The neurosurgical anatomy of the sphenoid sinus and sellar floor in endoscopic transsphenoidal surgery.
Authors: Authors: Zada G, Agarwalla PK, Mukundan S, Dunn I, Golby AJ, Laws ER.
J Neurosurg
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Neurosurgery Clinics of North America. Functional imaging. Preface.
Authors: Authors: Golby AJ, McLaren Black P.
Neurosurg Clin N Am
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Multimodal image registration for preoperative planning and image-guided neurosurgical procedures.
Authors: Authors: Risholm P, Golby AJ, Wells W.
Neurosurg Clin N Am
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Development of a clinical functional magnetic resonance imaging service.
Authors: Authors: Rigolo L, Stern E, Deaver P, Golby AJ, Mukundan S.
Neurosurg Clin N Am
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Special surgical considerations for functional brain mapping.
Authors: Authors: Kekhia H, Rigolo L, Norton I, Golby AJ.
Neurosurg Clin N Am
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A new metric for detecting change in slowly evolving brain tumors: validation in meningioma patients.
Authors: Authors: Pohl KM, Konukoglu E, Novellas S, Ayache N, Fedorov A, Talos IF, Golby A, Wells WM, Kikinis R, Black PM.
Neurosurgery
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Development of stereotactic mass spectrometry for brain tumor surgery.
Authors: Authors: Agar NY, Golby AJ, Ligon KL, Norton I, Mohan V, Wiseman JM, Tannenbaum A, Jolesz FA.
Neurosurgery
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Interactive diffusion tensor tractography visualization for neurosurgical planning.
Authors: Authors: Golby AJ, Kindlmann G, Norton I, Yarmarkovich A, Pieper S, Kikinis R.
Neurosurgery
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