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Alexandra Golby, MD

Professor of Neurosurgery, Harvard Medical School
Professor of Radiology, Harvard Medical School
Department of Global Health and Social Medicine Affiliate
Haley Distinguished Chair in the Neurosciences, Brigham and Women's Hospital
Senior Surgeon, Brigham and Women's Hospital
Director of Image-guided Neurosurgery, Brigham and Women's Hospital
Co-Director AMIGO, Brigham and Women's Hospital

Dr. Golby is a Neurosurgeon and Haley Distinguished Chair in the Neurosciences at Brigham and Women’s Hospital in Boston. She is Professor of Neurosurgery and Professor of Radiology at Harvard Medical School.  She is also Principal Investigator of the Golby Lab, a surgical brain mapping laboratory. Dr. Golby’s clinical focus is on brain surgery for patients with brain tumors and epilepsy, especially those lesions which are intimately associated with critical brain structures. Her translational research is focused on advanced imaging and image guidance to improve care for patients undergoing intracranial neurosurgery. She has developed numerous technologies to help guide presurgical planning and intraoperative decision-making. She works closely with scientists across disciplines including computer science, applied mathematics, MR and ultrasound physics, radiology, neuroscience, and biomedical engineering. She is very involved with mentoring young clinicians and scientists both locally and globally. Dr. Golby was recently a Fulbright Global Scholar pursuing work to foster interdisciplinary collaborations between technical experts and clinicians in host countries Rwanda and Morocco to develop innovative medical technology suited to local conditions.

Dr. Golby received her BA from Yale University and MD from Stanford University School of Medicine. She completed residency training in Neurosurgery at Brigham and Women’s Hospital.

The Golby Lab is a multidisciplinary team of investigators using advanced imaging, image analysis, and computational strategies to develop novel approaches to guide neurosurgery. Areas of interest include using functional MRI to map cortical organization and diffusion MRI to map white matter connections, intra-operative imaging, navigation and guidance, and image guided therapies for brain tumors. She is the co-director of AMIGO, the advanced multi-modality Image guided OR, an NIH-funded translational research operating suite where surgeons and interventionalists work with radiologists and technical experts to develop novel therapies to provide precise, minimally invasive, and effective treatments to patients. She leads the development of NousNav a low-cost open-source neuronavigation system for use in resource-limited settings.

Hybrid formulation of the model-based non-rigid registration problem to improve accuracy and robustness.
Authors: Authors: Clatz O, Delingette H, Talos IF, Golby AJ, Kikinis R, Jolesz FA, Ayache N, Warfield SK.
Med Image Comput Comput Assist Interv
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Krishnan et al
Authors: Authors: Comment on: Functional magnetic resonance imaging integrated neuronavigation: Correlation between lesion-to-motor cortex distance and outcome
Neurosurgery
Evaluating requirements for spatial resolution of fMRI for neurosurgical planning.
Authors: Authors: Yoo SS, Talos IF, Golby AJ, Black PM, Panych LP.
Hum Brain Mapp
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Memory lateralization in medial temporal lobe epilepsy assessed by functional MRI.
Authors: Authors: Golby AJ, Poldrack RA, Illes J, Chen D, Desmond JE, Gabrieli JD.
Epilepsia
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Minimalist approach: functional mapping.
Authors: Authors: Black P, Jaaskelainen J, Chabrerie A, Golby A, Gugino L.
Clin Neurosurg
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Material-specific lateralization in the medial temporal lobe and prefrontal cortex during memory encoding.
Authors: Authors: Golby AJ, Poldrack RA, Brewer JB, Spencer D, Desmond JE, Aron AP, Gabrieli JD.
Brain
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Differential responses in the fusiform region to same-race and other-race faces.
Authors: Authors: Golby AJ, Gabrieli JD, Chiao JY, Eberhardt JL.
Nat Neurosci
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Fractionated stereotactic radiosurgery and preservation of hearing in patients with vestibular schwannoma: a preliminary report.
Authors: Authors: Poen JC, Golby AJ, Forster KM, Martin DP, Chinn DM, Hancock SL, Adler JR.
Neurosurgery
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Direct and combined revascularization in pediatric moyamoya disease.
Authors: Authors: Golby AJ, Marks MP, Thompson RC, Steinberg GK.
Neurosurgery
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Trigeminal neuralgia resulting from infarction of the root entry zone of the trigeminal nerve: case report.
Authors: Authors: Golby AJ, Norbash A, Silverberg GD.
Neurosurgery
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