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Alexandra Golby, MD

Professor of Neurosurgery, Harvard Medical School
Professor of Radiology, Harvard Medical School
Department of Global Health and Social Medicine Affiliate
Haley Distinguished Chair in the Neurosciences, Brigham and Women's Hospital
Senior Surgeon, Brigham and Women's Hospital
Director of Image-guided Neurosurgery, Brigham and Women's Hospital
Co-Director AMIGO, Brigham and Women's Hospital

Dr. Golby is a Neurosurgeon and Haley Distinguished Chair in the Neurosciences at Brigham and Women’s Hospital in Boston. She is Professor of Neurosurgery and Professor of Radiology at Harvard Medical School.  She is also Principal Investigator of the Golby Lab, a surgical brain mapping laboratory. Dr. Golby’s clinical focus is on brain surgery for patients with brain tumors and epilepsy, especially those lesions which are intimately associated with critical brain structures. Her translational research is focused on advanced imaging and image guidance to improve care for patients undergoing intracranial neurosurgery. She has developed numerous technologies to help guide presurgical planning and intraoperative decision-making. She works closely with scientists across disciplines including computer science, applied mathematics, MR and ultrasound physics, radiology, neuroscience, and biomedical engineering. She is very involved with mentoring young clinicians and scientists both locally and globally. Dr. Golby was recently a Fulbright Global Scholar pursuing work to foster interdisciplinary collaborations between technical experts and clinicians in host countries Rwanda and Morocco to develop innovative medical technology suited to local conditions.

Dr. Golby received her BA from Yale University and MD from Stanford University School of Medicine. She completed residency training in Neurosurgery at Brigham and Women’s Hospital.

The Golby Lab is a multidisciplinary team of investigators using advanced imaging, image analysis, and computational strategies to develop novel approaches to guide neurosurgery. Areas of interest include using functional MRI to map cortical organization and diffusion MRI to map white matter connections, intra-operative imaging, navigation and guidance, and image guided therapies for brain tumors. She is the co-director of AMIGO, the advanced multi-modality Image guided OR, an NIH-funded translational research operating suite where surgeons and interventionalists work with radiologists and technical experts to develop novel therapies to provide precise, minimally invasive, and effective treatments to patients. She leads the development of NousNav a low-cost open-source neuronavigation system for use in resource-limited settings.

Tractography methods and findings in brain tumors and traumatic brain injury.
Authors: Authors: Yeh FC, Irimia A, Bastos DCA, Golby AJ.
Neuroimage
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Tractography dissection variability: What happens when 42 groups dissect 14 white matter bundles on the same dataset?
Authors: Authors: Schilling KG, Rheault F, Petit L, Hansen CB, Nath V, Yeh FC, Girard G, Barakovic M, Rafael-Patino J, Yu T, Fischi-Gomez E, Pizzolato M, Ocampo-Pineda M, Schiavi S, Canales-Rodríguez EJ, Daducci A, Granziera C, Innocenti G, Thiran JP, Mancini L, Wastling S, Cocozza S, Petracca M, Pontillo G, Mancini M, Vos SB, Vakharia VN, Duncan JS, Melero H, Manzanedo L, Sanz-Morales E, Peña-Melián Á, Calamante F, Attyé A, Cabeen RP, Korobova L, Toga AW, Vijayakumari AA, Parker D, Verma R, Radwan A, Sunaert S, Emsell L, De Luca A, Leemans A, Bajada CJ, Haroon H, Azadbakht H, Chamberland M, Genc S, Tax CMW, Yeh PH, Srikanchana R, Mcknight CD, Yang JY, Chen J, Kelly CE, Yeh CH, Cochereau J, Maller JJ, Welton T, Almairac F, Seunarine KK, Clark CA, Zhang F, Makris N, Golby A, Rathi Y, O'Donnell LJ, Xia Y, Aydogan DB, Shi Y, Fernandes FG, Raemaekers M, Warrington S, Michielse S, Ramírez-Manzanares A, Concha L, Aranda R, Meraz MR, Lerma-Usabiaga G, Roitman L, Fekonja LS, Calarco N, Joseph M, Nakua H, Voineskos AN, Karan P, Grenier G, Legarreta JH, Adluru N, Nair VA, Prabhakaran V, Alexander AL, Kamagata K, Saito Y, Uchida W, Andica C, Abe M, Bayrak RG, Wheeler-Kingshott CAMG, D'Angelo E, Palesi F, Savini G, Rolandi N, Guevara P, Houenou J, López-López N, Mangin JF, Poupon C, Román C, Vázquez A, Maffei C, Arantes M, Andrade JP, Silva SM, Calhoun VD, Caverzasi E, Sacco S, Lauricella M, Pestilli F, Bullock D, Zhan Y, Brignoni-Perez E, Lebel C, Reynolds JE, Nestrasil I, Labounek R, Lenglet C, Paulson A, Aulicka S, Heilbronner SR, Heuer K, Chandio BQ, Guaje J, Tang W, Garyfallidis E, Raja R, Anderson AW, Landman BA, Descoteaux M.
Neuroimage
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Comparison of multiple tractography methods for reconstruction of the retinogeniculate visual pathway using diffusion MRI.
Authors: Authors: He J, Zhang F, Xie G, Yao S, Feng Y, Bastos DCA, Rathi Y, Makris N, Kikinis R, Golby AJ, O'Donnell LJ.
Hum Brain Mapp
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Enhancement of semantic integration reasoning by tRNS.
Authors: Authors: Sprugnoli G, Rossi S, Liew SL, Bricolo E, Costantini G, Salvi C, Golby AJ, Musaeus CS, Pascual-Leone A, Rossi A, Santarnecchi E.
Cogn Affect Behav Neurosci
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Personalised, image-guided, noninvasive brain stimulation in gliomas: Rationale, challenges and opportunities.
Authors: Authors: Sprugnoli G, Rossi S, Rotenberg A, Pascual-Leone A, El-Fakhri G, Golby AJ, Santarnecchi E.
EBioMedicine
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Estimation of High Framerate Digital Subtraction Angiography Sequences at Low Radiation Dose.
Authors: Authors: Haouchine N, Juvekar P, Xiong X, Luo J, Kapur T, Du R, Golby A, Frisken S.
Med Image Comput Comput Assist Interv
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Newly discovered neuron-to-glioma communication: new noninvasive therapeutic opportunities on the horizon?
Authors: Authors: Sprugnoli G, Golby AJ, Santarnecchi E.
Neurooncol Adv
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Biopsy Artifact in Laser Interstitial Thermal Therapy: A Technical Note.
Authors: Authors: Noh T, Juvekar P, Huang R, Lee G, Ogasawara CT, Golby AJ.
Front Oncol
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Intraoperative Imaging for High-Grade Glioma Surgery.
Authors: Authors: Noh T, Mustroph M, Golby AJ.
Neurosurg Clin N Am
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Challenges and Opportunities of Intraoperative 3D Ultrasound With Neuronavigation in Relation to Intraoperative MRI.
Authors: Authors: Bastos DCA, Juvekar P, Tie Y, Jowkar N, Pieper S, Wells WM, Bi WL, Golby A, Frisken S, Kapur T.
Front Oncol
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