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Alexandra Golby, MD

Professor of Neurosurgery, Harvard Medical School
Professor of Radiology, Harvard Medical School
Department of Global Health and Social Medicine Affiliate
Haley Distinguished Chair in the Neurosciences, Brigham and Women's Hospital
Senior Surgeon, Brigham and Women's Hospital
Director of Image-guided Neurosurgery, Brigham and Women's Hospital
Co-Director AMIGO, Brigham and Women's Hospital

Dr. Golby is a Neurosurgeon and Haley Distinguished Chair in the Neurosciences at Brigham and Women’s Hospital in Boston. She is Professor of Neurosurgery and Professor of Radiology at Harvard Medical School.  She is also Principal Investigator of the Golby Lab, a surgical brain mapping laboratory. Dr. Golby’s clinical focus is on brain surgery for patients with brain tumors and epilepsy, especially those lesions which are intimately associated with critical brain structures. Her translational research is focused on advanced imaging and image guidance to improve care for patients undergoing intracranial neurosurgery. She has developed numerous technologies to help guide presurgical planning and intraoperative decision-making. She works closely with scientists across disciplines including computer science, applied mathematics, MR and ultrasound physics, radiology, neuroscience, and biomedical engineering. She is very involved with mentoring young clinicians and scientists both locally and globally. Dr. Golby was recently a Fulbright Global Scholar pursuing work to foster interdisciplinary collaborations between technical experts and clinicians in host countries Rwanda and Morocco to develop innovative medical technology suited to local conditions.

Dr. Golby received her BA from Yale University and MD from Stanford University School of Medicine. She completed residency training in Neurosurgery at Brigham and Women’s Hospital.

The Golby Lab is a multidisciplinary team of investigators using advanced imaging, image analysis, and computational strategies to develop novel approaches to guide neurosurgery. Areas of interest include using functional MRI to map cortical organization and diffusion MRI to map white matter connections, intra-operative imaging, navigation and guidance, and image guided therapies for brain tumors. She is the co-director of AMIGO, the advanced multi-modality Image guided OR, an NIH-funded translational research operating suite where surgeons and interventionalists work with radiologists and technical experts to develop novel therapies to provide precise, minimally invasive, and effective treatments to patients. She leads the development of NousNav a low-cost open-source neuronavigation system for use in resource-limited settings.

Fiber clustering versus the parcellation-based connectome.
Authors: Authors: O'Donnell LJ, Golby AJ, Westin CF.
Neuroimage
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Rapid, label-free detection of brain tumors with stimulated Raman scattering microscopy.
Authors: Authors: Ji M, Orringer DA, Freudiger CW, Ramkissoon S, Liu X, Lau D, Golby AJ, Norton I, Hayashi M, Agar NY, Young GS, Spino C, Santagata S, Camelo-Piragua S, Ligon KL, Sagher O, Xie XS.
Sci Transl Med
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Hemispheric lateralization interrupted: material-specific memory deficits in temporal lobe epilepsy.
Authors: Authors: Willment KC, Golby A.
Front Hum Neurosci
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Effect of disease and recovery on functional anatomy in brain tumor patients: insights from functional MRI and diffusion tensor imaging.
Authors: Authors: Abd-El-Barr MM, Saleh E, Huang RY, Golby AJ.
Imaging Med
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Extended Broca's area in the functional connectome of language in adults: combined cortical and subcortical single-subject analysis using fMRI and DTI tractography.
Authors: Authors: Lemaire JJ, Golby A, Wells WM, Pujol S, Tie Y, Rigolo L, Yarmarkovich A, Pieper S, Westin CF, Jolesz F, Kikinis R.
Brain Topogr
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Bayesian characterization of uncertainty in intra-subject non-rigid registration.
Authors: Authors: Risholm P, Janoos F, Norton I, Golby AJ, Wells WM.
Med Image Anal
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Functional and structural differences in the hippocampus associated with memory deficits in adult survivors of acute lymphoblastic leukemia.
Authors: Authors: Monje M, Thomason ME, Rigolo L, Wang Y, Waber DP, Sallan SE, Golby AJ.
Pediatr Blood Cancer
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Ambient mass spectrometry for the intraoperative molecular diagnosis of human brain tumors.
Authors: Authors: Eberlin LS, Norton I, Orringer D, Dunn IF, Liu X, Ide JL, Jarmusch AK, Ligon KL, Jolesz FA, Golby AJ, Santagata S, Agar NY, Cooks RG.
Proc Natl Acad Sci U S A
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GBM volumetry using the 3D Slicer medical image computing platform.
Authors: Authors: Egger J, Kapur T, Fedorov A, Pieper S, Miller JV, Veeraraghavan H, Freisleben B, Golby AJ, Nimsky C, Kikinis R.
Sci Rep
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Surgery, virtual reality, and the future.
Authors: Authors: Vosburgh KG, Golby A, Pieper SD.
Stud Health Technol Inform
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