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Alexandra Golby, MD

Professor of Neurosurgery, Harvard Medical School
Professor of Radiology, Harvard Medical School
Department of Global Health and Social Medicine Affiliate
Haley Distinguished Chair in the Neurosciences, Brigham and Women's Hospital
Senior Surgeon, Brigham and Women's Hospital
Director of Image-guided Neurosurgery, Brigham and Women's Hospital
Co-Director AMIGO, Brigham and Women's Hospital

Dr. Golby is a Neurosurgeon and Haley Distinguished Chair in the Neurosciences at Brigham and Women’s Hospital in Boston. She is Professor of Neurosurgery and Professor of Radiology at Harvard Medical School.  She is also Principal Investigator of the Golby Lab, a surgical brain mapping laboratory. Dr. Golby’s clinical focus is on brain surgery for patients with brain tumors and epilepsy, especially those lesions which are intimately associated with critical brain structures. Her translational research is focused on advanced imaging and image guidance to improve care for patients undergoing intracranial neurosurgery. She has developed numerous technologies to help guide presurgical planning and intraoperative decision-making. She works closely with scientists across disciplines including computer science, applied mathematics, MR and ultrasound physics, radiology, neuroscience, and biomedical engineering. She is very involved with mentoring young clinicians and scientists both locally and globally. Dr. Golby was recently a Fulbright Global Scholar pursuing work to foster interdisciplinary collaborations between technical experts and clinicians in host countries Rwanda and Morocco to develop innovative medical technology suited to local conditions.

Dr. Golby received her BA from Yale University and MD from Stanford University School of Medicine. She completed residency training in Neurosurgery at Brigham and Women’s Hospital.

The Golby Lab is a multidisciplinary team of investigators using advanced imaging, image analysis, and computational strategies to develop novel approaches to guide neurosurgery. Areas of interest include using functional MRI to map cortical organization and diffusion MRI to map white matter connections, intra-operative imaging, navigation and guidance, and image guided therapies for brain tumors. She is the co-director of AMIGO, the advanced multi-modality Image guided OR, an NIH-funded translational research operating suite where surgeons and interventionalists work with radiologists and technical experts to develop novel therapies to provide precise, minimally invasive, and effective treatments to patients. She leads the development of NousNav a low-cost open-source neuronavigation system for use in resource-limited settings.

Pneumatically driven finger movement: a novel passive functional MR imaging technique for presurgical motor and sensory mapping.
Authors: Authors: Shriver S, Knierim KE, O'Shea JP, Glover GH, Golby AJ.
AJNR Am J Neuroradiol
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Temporal stability of visually selective responses in intracranial field potentials recorded from human occipital and temporal lobes.
Authors: Authors: Bansal AK, Singer JM, Anderson WS, Golby A, Madsen JR, Kreiman G.
J Neurophysiol
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Clinical applications and future directions of functional MRI.
Authors: Authors: Orringer DA, Vago DR, Golby AJ.
Semin Neurol
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Neuronavigation in the surgical management of brain tumors: current and future trends.
Authors: Authors: Orringer DA, Golby A, Jolesz F.
Expert Rev Med Devices
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Outcomes after discontinuation of antiepileptic drugs after surgery in patients with low grade brain tumors and meningiomas.
Authors: Authors: Das RR, Artsy E, Hurwitz S, Wen PY, Black P, Golby A, Dworetzky B, Lee JW.
J Neurooncol
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fMRI-DTI modeling via landmark distance atlases for prediction and detection of fiber tracts.
Authors: Authors: O'Donnell LJ, Rigolo L, Norton I, Wells WM, Westin CF, Golby AJ.
Neuroimage
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Visual pathway study using in vivo diffusion tensor imaging tractography to complement classic anatomy.
Authors: Authors: Wu W, Rigolo L, O'Donnell LJ, Norton I, Shriver S, Golby AJ.
Neurosurgery
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Classifying human brain tumors by lipid imaging with mass spectrometry.
Authors: Authors: Eberlin LS, Norton I, Dill AL, Golby AJ, Ligon KL, Santagata S, Cooks RG, Agar NY.
Cancer Res
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Chiasmal visual loss after retinal detachment.
Authors: Authors: Prasad S, Golby A.
Neurology
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PTFOS: flexible and absorbable intracranial electrodes for magnetic resonance imaging.
Authors: Authors: Bonmassar G, Fujimoto K, Golby AJ.
PLoS One
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