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Alexandra Golby, MD

Professor of Neurosurgery, Harvard Medical School
Professor of Radiology, Harvard Medical School
Department of Global Health and Social Medicine Affiliate
Haley Distinguished Chair in the Neurosciences, Brigham and Women's Hospital
Senior Surgeon, Brigham and Women's Hospital
Director of Image-guided Neurosurgery, Brigham and Women's Hospital
Co-Director AMIGO, Brigham and Women's Hospital

Dr. Golby is a Neurosurgeon and Haley Distinguished Chair in the Neurosciences at Brigham and Women’s Hospital in Boston. She is Professor of Neurosurgery and Professor of Radiology at Harvard Medical School.  She is also Principal Investigator of the Golby Lab, a surgical brain mapping laboratory. Dr. Golby’s clinical focus is on brain surgery for patients with brain tumors and epilepsy, especially those lesions which are intimately associated with critical brain structures. Her translational research is focused on advanced imaging and image guidance to improve care for patients undergoing intracranial neurosurgery. She has developed numerous technologies to help guide presurgical planning and intraoperative decision-making. She works closely with scientists across disciplines including computer science, applied mathematics, MR and ultrasound physics, radiology, neuroscience, and biomedical engineering. She is very involved with mentoring young clinicians and scientists both locally and globally. Dr. Golby was recently a Fulbright Global Scholar pursuing work to foster interdisciplinary collaborations between technical experts and clinicians in host countries Rwanda and Morocco to develop innovative medical technology suited to local conditions.

Dr. Golby received her BA from Yale University and MD from Stanford University School of Medicine. She completed residency training in Neurosurgery at Brigham and Women’s Hospital.

The Golby Lab is a multidisciplinary team of investigators using advanced imaging, image analysis, and computational strategies to develop novel approaches to guide neurosurgery. Areas of interest include using functional MRI to map cortical organization and diffusion MRI to map white matter connections, intra-operative imaging, navigation and guidance, and image guided therapies for brain tumors. She is the co-director of AMIGO, the advanced multi-modality Image guided OR, an NIH-funded translational research operating suite where surgeons and interventionalists work with radiologists and technical experts to develop novel therapies to provide precise, minimally invasive, and effective treatments to patients. She leads the development of NousNav a low-cost open-source neuronavigation system for use in resource-limited settings.

Predicted Microscopic Cortical Brain Images for Optimal Craniotomy Positioning and Visualization.
Authors: Authors: Haouchine N, Juvekar P, Golby A, Frisken S.
Comput Methods Biomech Biomed Eng Imaging Vis
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Reactivation of Motor-Related Gamma Activity in Human NREM Sleep.
Authors: Authors: Eichenlaub JB, Biswal S, Peled N, Rivilis N, Golby AJ, Lee JW, Westover MB, Halgren E, Cash SS.
Front Neurosci
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REVIEW: MR elastography of brain tumors.
Authors: Authors: Bunevicius A, Schregel K, Sinkus R, Golby A, Patz S.
Neuroimage Clin
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Adaptive Physics-Based Non-Rigid Registration for Immersive Image-Guided Neuronavigation Systems.
Authors: Authors: Drakopoulos F, Tsolakis C, Angelopoulos A, Liu Y, Yao C, Kavazidi KR, Foroglou N, Fedorov A, Frisken S, Kikinis R, Golby A, Chrisochoides N.
Front Digit Health
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Neural Interactions Underlying Visuomotor Associations in the Human Brain.
Authors: Authors: Madhavan R, Bansal AK, Madsen JR, Golby AJ, Tierney TS, Eskandar EN, Anderson WS, Kreiman G.
Cereb Cortex
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Deformable MRI-Ultrasound registration using correlation-based attribute matching for brain shift correction: Accuracy and generality in multi-site data.
Authors: Authors: Machado I, Toews M, George E, Unadkat P, Essayed W, Luo J, Teodoro P, Carvalho H, Martins J, Golland P, Pieper S, Frisken S, Golby A, Wells Iii W, Ou Y.
Neuroimage
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Deep white matter analysis: fast, consistent tractography segmentation across populations and dMRI acquisitions.
Authors: Authors: Zhang F, Hoffmann N, Karayumak SC, Rathi Y, Golby AJ, O'Donnell LJ.
Med Image Comput Comput Assist Interv
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Commentary: Extent of Resection and Residual Tumor Thresholds for Postoperative Total Seizure Freedom in Epileptic Adult Patients Harboring a Supratentorial Diffuse Low-Grade Glioma.
Authors: Authors: Valdes PA, Golby AJ.
Neurosurgery
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Test-retest reproducibility of white matter parcellation using diffusion MRI tractography fiber clustering.
Authors: Authors: Zhang F, Wu Y, Norton I, Rathi Y, Golby AJ, O'Donnell LJ.
Hum Brain Mapp
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Frameless Stereotactic Navigation during Insular Glioma Resection using Fusion of Three-Dimensional Rotational Angiography and Magnetic Resonance Imaging.
Authors: Authors: Dasenbrock HH, See AP, Smalley RJ, Bi WL, Dolati P, Frerichs KU, Golby AJ, Chiocca EA, Aziz-Sultan MA.
World Neurosurg
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