Image of Alexandra Golby

Alexandra Golby, MD

Professor of Neurosurgery, Harvard Medical School
Professor of Radiology, Harvard Medical School
Department of Global Health and Social Medicine Affiliate
Haley Distinguished Chair in the Neurosciences, Brigham and Women's Hospital
Senior Surgeon, Brigham and Women's Hospital
Director of Image-guided Neurosurgery, Brigham and Women's Hospital
Co-Director AMIGO, Brigham and Women's Hospital

Dr. Golby is a Neurosurgeon and Haley Distinguished Chair in the Neurosciences at Brigham and Women’s Hospital in Boston. She is Professor of Neurosurgery and Professor of Radiology at Harvard Medical School.  She is also Principal Investigator of the Golby Lab, a surgical brain mapping laboratory. Dr. Golby’s clinical focus is on brain surgery for patients with brain tumors and epilepsy, especially those lesions which are intimately associated with critical brain structures. Her translational research is focused on advanced imaging and image guidance to improve care for patients undergoing intracranial neurosurgery. She has developed numerous technologies to help guide presurgical planning and intraoperative decision-making. She works closely with scientists across disciplines including computer science, applied mathematics, MR and ultrasound physics, radiology, neuroscience, and biomedical engineering. She is very involved with mentoring young clinicians and scientists both locally and globally. Dr. Golby was recently a Fulbright Global Scholar pursuing work to foster interdisciplinary collaborations between technical experts and clinicians in host countries Rwanda and Morocco to develop innovative medical technology suited to local conditions.

Dr. Golby received her BA from Yale University and MD from Stanford University School of Medicine. She completed residency training in Neurosurgery at Brigham and Women’s Hospital.

The Golby Lab is a multidisciplinary team of investigators using advanced imaging, image analysis, and computational strategies to develop novel approaches to guide neurosurgery. Areas of interest include using functional MRI to map cortical organization and diffusion MRI to map white matter connections, intra-operative imaging, navigation and guidance, and image guided therapies for brain tumors. She is the co-director of AMIGO, the advanced multi-modality Image guided OR, an NIH-funded translational research operating suite where surgeons and interventionalists work with radiologists and technical experts to develop novel therapies to provide precise, minimally invasive, and effective treatments to patients. She leads the development of NousNav a low-cost open-source neuronavigation system for use in resource-limited settings.

In: Neurosurgical Oncology
Authors: Authors: In Press: Malignant Cerebral Gliomas: treatment strategies and considerations
Black PM, Park J, Eds
MICCAI 2004: 7th International Conference, Proceedings, Part II
Authors: Authors: An Anisotropic Material Model for Image Guided Neurosurgery
2004; 267 – 275.
Proc Intl Soc Mag Reson Med
Authors: Authors: Quantification of white matter fiber orientation at tumor margins with diffusion tensor invariant gradients
2008.
MICCAI
Authors: Authors: Hybrid Formulation of the Model-Based Non-rigid Registration Problem to Improve Accuracy and Robustness
2005; (2):295-302.
ICCS 2007: International Conference on Computer Science
Authors: Authors: Grid-Enabled Software Environment for Enhanced Dynamic Data-Driven Visualization and Navigation during Image-Guided Neurosurgery
2007.
Journal of Immunology
Authors: Authors: Monoclonal Antibodies to Murine CD3 Define Distinct Epitopes, One of Which May Interact with CD4 During T-Cell Activation
1989; 142:4169-4175.
Congress of Neurological Surgeons 54th Annual Meeting
Authors: Authors: Pneumatically driven finger movement: a novel, passive fMRI technique for pre-surgical motor and sensory mapping
2004; 54th.
Int J of Med Robotics and Computer Assisted Surgery
Authors: Authors: Integrated image and function-guided surgery in eloquent cortex: A technique report
2006; 2:75-83.
Neurology
Authors: Authors: Neurologic Recovery from Vegetative State Following Cardiac Arrest
1995; 45(8):1629-30.
2008.
Authors: Authors: Identification of Essential Language Areas by Combination of fMRI from Different Tasks using Probabilistic Independent Component Analysis