Molly F

Molly Forrest Franke, SD

Professor, Department of Global Health and Social Medicine, Harvard Medical School
Associate Professor, Department of Epidemiology, Harvard T.H. Chan School of Public Health
Epidemiologist, Global Health Research Core

Molly F. Franke, ScD, completed undergraduate studies in Sociology and Spanish at Colby College and doctoral training in Epidemiology at the Harvard T.H. Chan School of Public Health. Prior to joining the Department, she worked for the Massachusetts Department of Public Health Epidemiology & Immunization Surveillance Program and Partners In Health in Peru and Rwanda. She is a long-time volunteer with the Elm Project, which supports underserved youth affected by chronic illness.

Professor Franke serves as Co-Director of Harvard University Centers for AIDS Research Developmental and Mentoring Core and is an active mentor in the Harvard Medical School Masters of Medical Sciences in Global Health Delivery (MMSc-GHD) program, serving on the Curriculum and Admissions Committees. Throughout her career, Professor Franke has contributed to the learning of dozens of students and trainees within the Harvard community, at other institutions of higher learning, and in the places where she conducts research. She has been recognized for excellence in mentoring: in 2017, she received the Jo Rae Wright Award for promising contributions to pulmonary research along with outstanding mentoring and professional leadership qualities, and in 2020, she was awarded the Young Mentor Award by Harvard Medical School.

Professor Franke is a global health researcher whose work brings the rigor of epidemiology to intractable infections (tuberculosis, cholera, HIV, SARS-CoV-2) and chronic diseases (diabetes, hypertension, depression). Her work has spanned a range of settings including Peru, Haiti, Rwanda, Lesotho, Papua New Guinea, and the United States.

Franke’s current work has two broad objectives. The first is to improve the health of children and adolescents affected by TB and HIV. She leads intervention work in Peru that aims to improve the treatment outcomes and overall well-being of adolescents and young adults living with HIV through the provision of community-based support and through youth-friendly modalities, such as social media. The second objective of her work is to ensure that care and treatment of health conditions that disproportionately affect the poor and socially marginalized are guided by the highest possible quality of evidence. To this end, she seeks to identify and apply the best epidemiologic methods for addressing critical knowledge gaps related to interventions and treatment.  Examples of her work in this area include the design of robust studies to assess the effectiveness of cholera interventions, including vaccination, and the use of causal inference-based approaches to study treatment for drug-resistant tuberculosis.

Detection of Mycobacterium tuberculosis transrenal DNA in urine samples among adult patients in Peru.
Authors: Authors: Mesman AW, Calderon RI, Hauns L, Pollock NR, Mendoza M, Holmberg RC, Franke MF.
medRxiv
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Respiratory, Cardiac, and Neuropsychiatric Manifestations of Postacute Sequelae of Coronavirus Disease 2019 in Lima, Peru.
Authors: Authors: Rahman RS, Tovar MA, Peinado J, Palomino JS, Ramirez C, Llanos-Zavalaga F, Peralta E, Valderrama G, Ramos Cordova LB, Sanchez Cortez LI, Rodriguez G, LaHood AN, Franke MF, Mitnick CD, Lecca L, Velásquez GE.
Open Forum Infect Dis
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Poor Sensitivity of Stool Culture Compared to Polymerase Chain Reaction in Surveillance for Vibrio cholerae in Haiti, 2018-2019.
Authors: Authors: Guillaume Y, Debela M, Slater D, Vissieres K, Ternier R, Franke MF, Harris JB, Ivers LC.
Open Forum Infect Dis
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Effectiveness of Bedaquiline Use beyond Six Months in Patients with Multidrug-Resistant Tuberculosis.
Authors: Authors: Trevisi L, Hernán MA, Mitnick CD, Khan U, Seung KJ, Rich ML, Bastard M, Huerga H, Melikyan N, Atwood SA, Avaliani Z, Llanos F, Manzur-Ul-Alam M, Zarli K, Binegdie AB, Adnan S, Melikyan A, Gelin A, Isani AK, Vetushko D, Daugarina Z, Nkundanyirazo P, Putri FA, Vilbrun C, Khan M, Hewison C, Khan PY, Franke MF.
Am J Respir Crit Care Med
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Outcomes of WHO-conforming, longer, all-oral multidrug-resistant TB regimens and analysis implications.
Authors: Authors: Rich ML, Khan U, Zeng C, LaHood A, Franke MF, Atwood S, Bastard M, Burhan E, Danielyan N, Dzhazibekova PM, Gadissa D, Ghafoor A, Hewison C, Islam MS, Kazmi E, Khan PY, Lecca L, Maama LB, Melikyan N, Naing YY, Philippe K, Saki NA, Seung KJ, Skrahina A, Tefera GB, Varaine F, Vilbrun SC, Võ L, Mitnick CD, Huerga H.
Int J Tuberc Lung Dis
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Estimating post-treatment recurrence after multidrug-resistant tuberculosis treatment among patients with and without HIV: the impact of assumptions about death and missing follow-up.
Authors: Authors: Sauer SM, Mitnick CD, Khan U, Hewison C, Bastard M, Holtzman D, Law S, Khan M, Padayachee S, Ahmed S, Isani AK, Krisnanda A, Vilbrun SC, Bektasov S, Kumsa A, Docteur W, Tintaya K, McNicol M, Atshemyan H, Voynilo T, Thwe TT, Seung K, Rich M, Huerga H, Khan P, Franke M.
medRxiv
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Development of treatment-decision algorithms for children evaluated for pulmonary tuberculosis: an individual participant data meta-analysis.
Authors: Authors: Gunasekera KS, Marcy O, Muñoz J, Lopez-Varela E, Sekadde MP, Franke MF, Bonnet M, Ahmed S, Amanullah F, Anwar A, Augusto O, Aurilio RB, Banu S, Batool I, Brands A, Cain KP, Carratalá-Castro L, Caws M, Click ES, Cranmer LM, García-Basteiro AL, Hesseling AC, Huynh J, Kabir S, Lecca L, Mandalakas A, Mavhunga F, Myint AA, Myo K, Nampijja D, Nicol MP, Orikiriza P, Palmer M, Sant'Anna CC, Siddiqui SA, Smith JP, Song R, Thuong Thuong NT, Ung V, van der Zalm MM, Verkuijl S, Viney K, Walters EG, Warren JL, Zar HJ, Marais BJ, Graham SM, Debray TPA, Cohen T, Seddon JA.
Lancet Child Adolesc Health
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Low detection rate of RT-PCR-confirmed COVID-19 using IgM/IgG rapid antibody tests in a large community sample in Lima, Peru.
Authors: Authors: Law S, Tovar MA, Franke MF, Calderon R, Palomino S, Valderrama G, Llanos F, Velásquez GE, Mitnick CD, Lecca L.
BMC Infect Dis
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Food insecurity and risk of cholera: A cross-sectional study and exploratory analysis of potential mediators.
Authors: Authors: Elnaiem AD, Franke MF, Richterman A, Guillaume Y, Vissieres K, Augustin GC, Ternier R, Ivers LC.
PLoS Negl Trop Dis
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Concordance of three approaches for operationalizing outcome definitions for multidrug-resistant TB.
Authors: Authors: Zeng C, Mitnick CD, Hewison C, Bastard M, Khan P, Seung KJ, Rich ML, Atwood S, Melikyan N, Morchiladze N, Khachatryan N, Khmyz M, Restrepo CG, Salahuddin N, Kazmi E, Dahri AA, Ahmed S, Varaine F, Vilbrun SC, Oyewusi L, Gelin A, Tintaya K, Yeraliyeva LT, Hamid S, Khan U, Huerga H, Franke MF.
Int J Tuberc Lung Dis
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