Molly F

Molly Forrest Franke, SD

Professor, Department of Global Health and Social Medicine, Harvard Medical School
Associate Professor, Department of Epidemiology, Harvard T.H. Chan School of Public Health
Epidemiologist, Global Health Research Core

Molly F. Franke, ScD, completed undergraduate studies in Sociology and Spanish at Colby College and doctoral training in Epidemiology at the Harvard T.H. Chan School of Public Health. Prior to joining the Department, she worked for the Massachusetts Department of Public Health Epidemiology & Immunization Surveillance Program and Partners In Health in Peru and Rwanda. She is a long-time volunteer with the Elm Project, which supports underserved youth affected by chronic illness.

Professor Franke serves as Co-Director of Harvard University Centers for AIDS Research Developmental and Mentoring Core and is an active mentor in the Harvard Medical School Masters of Medical Sciences in Global Health Delivery (MMSc-GHD) program, serving on the Curriculum and Admissions Committees. Throughout her career, Professor Franke has contributed to the learning of dozens of students and trainees within the Harvard community, at other institutions of higher learning, and in the places where she conducts research. She has been recognized for excellence in mentoring: in 2017, she received the Jo Rae Wright Award for promising contributions to pulmonary research along with outstanding mentoring and professional leadership qualities, and in 2020, she was awarded the Young Mentor Award by Harvard Medical School.

Professor Franke is a global health researcher whose work brings the rigor of epidemiology to intractable infections (tuberculosis, cholera, HIV, SARS-CoV-2) and chronic diseases (diabetes, hypertension, depression). Her work has spanned a range of settings including Peru, Haiti, Rwanda, Lesotho, Papua New Guinea, and the United States.

Franke’s current work has two broad objectives. The first is to improve the health of children and adolescents affected by TB and HIV. She leads intervention work in Peru that aims to improve the treatment outcomes and overall well-being of adolescents and young adults living with HIV through the provision of community-based support and through youth-friendly modalities, such as social media. The second objective of her work is to ensure that care and treatment of health conditions that disproportionately affect the poor and socially marginalized are guided by the highest possible quality of evidence. To this end, she seeks to identify and apply the best epidemiologic methods for addressing critical knowledge gaps related to interventions and treatment.  Examples of her work in this area include the design of robust studies to assess the effectiveness of cholera interventions, including vaccination, and the use of causal inference-based approaches to study treatment for drug-resistant tuberculosis.

The Impact of a Community-Based Intervention Including a Monthly Food Ration on Food Insecurity Among HIV-Positive Adults During the First Year of Antiretroviral Therapy.
Authors: Authors: Rothman J, Kayigamba F, Hills V, Gupta N, Machara F, Niyigena P, Franke MF.
AIDS Behav
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Vitamin E Status Is Inversely Associated with Risk of Incident Tuberculosis Disease among Household Contacts.
Authors: Authors: Aibana O, Franke MF, Huang CC, Galea JT, Calderon R, Zhang Z, Becerra MC, Smith ER, Contreras C, Yataco R, Lecca L, Murray MB.
J Nutr
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Automated TruTip nucleic acid extraction and purification from raw sputum.
Authors: Authors: Thakore N, Norville R, Franke M, Calderon R, Lecca L, Villanueva M, Murray MB, Cooney CG, Chandler DP, Holmberg RC.
PLoS One
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IL-6/IL-12 Cytokine Receptor Shuffling of Extra- and Intracellular Domains Reveals Canonical STAT Activation via Synthetic IL-35 and IL-39 Signaling.
Authors: Authors: Floss DM, Schönberg M, Franke M, Horstmeier FC, Engelowski E, Schneider A, Rosenfeldt EM, Scheller J.
Sci Rep
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Fluoroquinolone Resistance Mutation Detection Is Equivalent to Culture-Based Drug Sensitivity Testing for Predicting Multidrug-Resistant Tuberculosis Treatment Outcome: A Retrospective Cohort Study.
Authors: Authors: Farhat MR, Jacobson KR, Franke MF, Kaur D, Murray M, Mitnick CD.
Clin Infect Dis
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Development and Validation of a Food Frequency Questionnaire to Estimate Intake among Children and Adolescents in Urban Peru.
Authors: Authors: Rodriguez CA, Smith ER, Villamor E, Zavaleta N, Respicio-Torres G, Contreras C, Perea S, Jimenez J, Tintaya K, Lecca L, Murray MB, Franke MF.
Nutrients
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Comparison of two control groups for estimation of oral cholera vaccine effectiveness using a case-control study design.
Authors: Authors: Franke MF, Jerome JG, Matias WR, Ternier R, Hilaire IJ, Harris JB, Ivers LC.
Vaccine
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Increasing isoniazid preventive therapy uptake in an HIV program in rural Papua New Guinea.
Authors: Authors: Carmone A, Rodriguez CA, Frank TD, Kiromat M, Bongi PW, Kuno RG, Palou T, Franke MF.
Public Health Action
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Impact of Vitamin A and Carotenoids on the Risk of Tuberculosis Progression.
Authors: Authors: Aibana O, Franke MF, Huang CC, Galea JT, Calderon R, Zhang Z, Becerra MC, Smith ER, Ronnenberg AG, Contreras C, Yataco R, Lecca L, Murray MB.
Clin Infect Dis
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Validity and Utility of the Patient Health Questionnaire (PHQ)-2 and PHQ-9 for Screening and Diagnosis of Depression in Rural Chiapas, Mexico: A Cross-Sectional Study.
Authors: Authors: Arrieta J, Aguerrebere M, Raviola G, Flores H, Elliott P, Espinosa A, Reyes A, Ortiz-Panozo E, Rodriguez-Gutierrez EG, Mukherjee J, Palazuelos D, Franke MF.
J Clin Psychol
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