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Alexandra Golby, MD

Professor of Neurosurgery, Harvard Medical School
Professor of Radiology, Harvard Medical School
Department of Global Health and Social Medicine Affiliate
Haley Distinguished Chair in the Neurosciences, Brigham and Women's Hospital
Senior Surgeon, Brigham and Women's Hospital
Director of Image-guided Neurosurgery, Brigham and Women's Hospital
Co-Director AMIGO, Brigham and Women's Hospital

Dr. Golby is a Neurosurgeon and Haley Distinguished Chair in the Neurosciences at Brigham and Women’s Hospital in Boston. She is Professor of Neurosurgery and Professor of Radiology at Harvard Medical School.  She is also Principal Investigator of the Golby Lab, a surgical brain mapping laboratory. Dr. Golby’s clinical focus is on brain surgery for patients with brain tumors and epilepsy, especially those lesions which are intimately associated with critical brain structures. Her translational research is focused on advanced imaging and image guidance to improve care for patients undergoing intracranial neurosurgery. She has developed numerous technologies to help guide presurgical planning and intraoperative decision-making. She works closely with scientists across disciplines including computer science, applied mathematics, MR and ultrasound physics, radiology, neuroscience, and biomedical engineering. She is very involved with mentoring young clinicians and scientists both locally and globally. Dr. Golby was recently a Fulbright Global Scholar pursuing work to foster interdisciplinary collaborations between technical experts and clinicians in host countries Rwanda and Morocco to develop innovative medical technology suited to local conditions.

Dr. Golby received her BA from Yale University and MD from Stanford University School of Medicine. She completed residency training in Neurosurgery at Brigham and Women’s Hospital.

The Golby Lab is a multidisciplinary team of investigators using advanced imaging, image analysis, and computational strategies to develop novel approaches to guide neurosurgery. Areas of interest include using functional MRI to map cortical organization and diffusion MRI to map white matter connections, intra-operative imaging, navigation and guidance, and image guided therapies for brain tumors. She is the co-director of AMIGO, the advanced multi-modality Image guided OR, an NIH-funded translational research operating suite where surgeons and interventionalists work with radiologists and technical experts to develop novel therapies to provide precise, minimally invasive, and effective treatments to patients. She leads the development of NousNav a low-cost open-source neuronavigation system for use in resource-limited settings.

The emerging field of neurosurgical oncology: novel techniques to optimize outcomes and minimize mishaps.
Authors: Authors: Black P, Golby A, Johnson M.
Clin Neurosurg
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Object naming is a more sensitive measure of speech localization than number counting: Converging evidence from direct cortical stimulation and fMRI.
Authors: Authors: Petrovich Brennan NM, Whalen S, de Morales Branco D, O'shea JP, Norton IH, Golby AJ.
Neuroimage
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Functional MRI of memory in the hippocampus: Laterality indices may be more meaningful if calculated from whole voxel distributions.
Authors: Authors: Branco DM, Suarez RO, Whalen S, O'Shea JP, Nelson AP, da Costa JC, Golby AJ.
Neuroimage
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Integrated image- and function-guided surgery in eloquent cortex: a technique report.
Authors: Authors: O'Shea JP, Whalen S, Branco DM, Petrovich NM, Knierim KE, Golby AJ.
Int J Med Robot
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The brain basis for episodic memory: insights from functional MRI, intracranial EEG, and patients with epilepsy.
Authors: Authors: Hwang DY, Golby AJ.
Epilepsy Behav
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Image-guided neurosurgery at Brigham and Women's Hospital.
Authors: Authors: Dimaio SP, Archip N, Hata N, Talos IF, Warfield SK, Majumdar A, Mcdannold N, Hynynen K, Morrison PR, Wells WM, Kacher DF, Ellis RE, Golby AJ, Black PM, Jolesz FA, Kikinis R.
IEEE Eng Med Biol Mag
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Robust nonrigid registration to capture brain shift from intraoperative MRI.
Authors: Authors: Clatz O, Delingette H, Talos IF, Golby AJ, Kikinis R, Jolesz FA, Ayache N, Warfield SK.
IEEE Trans Med Imaging
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Atypical language representation in epilepsy: implications for injury-induced reorganization of brain function.
Authors: Authors: Goldmann RE, Golby AJ.
Epilepsy Behav
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Memory encoding in Alzheimer's disease: an fMRI study of explicit and implicit memory.
Authors: Authors: Golby A, Silverberg G, Race E, Gabrieli S, O'Shea J, Knierim K, Stebbins G, Gabrieli J.
Brain
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Capturing intraoperative deformations: research experience at Brigham and Women's Hospital.
Authors: Authors: Warfield SK, Haker SJ, Talos IF, Kemper CA, Weisenfeld N, Mewes AU, Goldberg-Zimring D, Zou KH, Westin CF, Wells WM, Tempany CM, Golby A, Black PM, Jolesz FA, Kikinis R.
Med Image Anal
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