Molly F

Molly Forrest Franke, SD

Associate Professor of Global Health and Social Medicine
Co-Director, Global and Community Health Advanced Integrated Science Course (AISC)
Epidemiologist, Global Health Research Core

Molly Franke is associate professor in the Department of Global Health and Social Medicine at Harvard Medical School. She co-directs the HMS Global and Community Health Advanced Integrated Science Course (AISC) and is a member of the Department’s Global Health Research Core.

Franke completed undergraduate studies in Sociology and Spanish at Colby College and doctoral training in Epidemiology at the Harvard T.H. Chan School of Public Health. Prior to joining the Department in 2010, she worked for Massachusetts Department of Public Health Epidemiology & Immunization Surveillance Program and Partners In Health sites in Peru and Rwanda. She is a long-time volunteer with the Elm Project, which supports underserved youth affected by chronic illness.

Throughout her career, Dr. Franke has contributed to the learning of dozens of students and trainees within the Harvard community, at other institutions of higher learning and the field sites where she conducts research. She is an active participant in the HMS Masters of Medical Sciences in Global Health Delivery (MMSc-GHD) program, serving as a thesis advisor and member of the Curriculum and Admissions Committees. She has been recognized for excellence in mentoring: in 2017 she received the Jo Rae Wright Award for promising contributions in pulmonary research along with outstanding mentoring and professional leadership qualities, and in 2020 she was awarded the Young Mentor Award by Harvard Medical School.

Dr. Franke is a global health researcher whose work brings the rigor of epidemiology to intractable infections (tuberculosis [TB], cholera, HIV, SARS-CoV-2) and chronic diseases (diabetes, hypertension depression) that disproportionately affect the poor or socially-marginalized. Her work has spanned a range of settings including Peru, Haiti, Rwanda, Mexico, Papua New Guinea, and the United States.

Franke’s current work has two broad objectives. The first is improve the health of children and adolescents affected by TB and HIV. She is the PI of a Peru-based pediatric tuberculosis diagnostic study that aims to identify the best non-sputum-based specimens from which to detect TB in children. She also leads intervention work in Peru that aims to improve the health and well-being of adolescents and young adults living with HIV through the provision of health navigation and social support and through youth-friendly modalities, such as music videos (https://vimeo.com/280933246).

The second objective of her work is to ensure that care and treatment of health conditions that disproportionately affect the poor and socially marginalized is guided by the highest possible quality of evidence. To this end, she seeks to identify and apply the best epidemiologic methods for addressing critical knowledge gaps related to interventions and treatment.  Her past work has included the development and validation of questionnaires; design of studies to assess the effectiveness of cholera interventions, including vaccination; and assessment of community-based programs for care and treatment of HIV, tuberculosis, mental health, diabetes and hypertension. Franke currently holds funding from the National Institutes of Health to improve the evidence base guiding treatment of drug-resistant TB through the application and adaptation of statistical methods commonly used in other fields.

Culture Conversion in Patients Treated with Bedaquiline and/or Delamanid. A Prospective Multicountry Study.
Authors: Authors: Franke MF, Khan P, Hewison C, Khan U, Huerga H, Seung KJ, Rich ML, Zarli K, Samieva N, Oyewusi L, Nair P, Mudassar M, Melikyan N, Lenggogeni P, Lecca L, Kumsa A, Khan M, Islam S, Hussein K, Docteur W, Chumburidze N, Berikova E, Atshemyan H, Atwood S, Alam M, Ahmed S, Bastard M, Mitnick CD.
Am J Respir Crit Care Med
View full abstract on Pubmed
[Impact of SARS-CoV-2 pandemic on adolescents living with HIV in Lima, Peru].
Authors: Authors: Errea RA, Wong M, Senador L, Ramos A, Ramos K, Galea JT, Lecca L, Sánchez H, Benites C, Franke MF.
Rev Peru Med Exp Salud Publica
View full abstract on Pubmed
Is exclusive breastfeeding for six-months protective against pediatric tuberculosis?
Authors: Authors: Flores JA, Coit J, Mendoza M, Leon SR, Konda K, Lecca L, Franke MF.
Glob Health Action
View full abstract on Pubmed
A non-specialist depression care pathway for adolescents living with HIV and transitioning into adult care in Peru: a nested, proof of concept pilot study.
Authors: Authors: Galea JT, Contreras C, Wong M, Ramos K, Vargas V, Sánchez H, Errea RA, Lecca L, Franke MF.
Glob Ment Health (Camb)
View full abstract on Pubmed
Molecular detection of Mycobacterium tuberculosis from buccal swabs among adult in Peru.
Authors: Authors: Mesman AW, Calderon RI, Pollock NR, Soto M, Mendoza M, Coit J, Zhang Z, Aliaga J, Lecca L, Holmberg RC, Franke MF.
Sci Rep
View full abstract on Pubmed
Uncovering reasons for treatment initiation delays among children with TB in Lima, Peru.
Authors: Authors: Coit J, Wong M, Galea JT, Mendoza M, Marin H, Tovar M, Chiang SS, Lecca L, Franke MF.
Int J Tuberc Lung Dis
View full abstract on Pubmed
Time for a change: considering regimen changes in analyses of observational drug-resistant TB treatment cohort data.
Authors: Authors: Franke MF, Mitnick CD.
Int J Tuberc Lung Dis
View full abstract on Pubmed
Detection of Mycobacterium Tuberculosis DNA in Buccal Swab Samples from Children in Lima, Peru.
Authors: Authors: Flores JA, Calderón R, Mesman AW, Soto M, Coit J, Aliaga J, Mendoza M, Leon SR, Konda K, Mestanza FM, Mendoza CJ, Lecca L, Murray MB, Holmberg RC, Pollock NR, Franke MF.
Pediatr Infect Dis J
View full abstract on Pubmed
Introducing new and repurposed TB drugs: the endTB experience.
Authors: Authors: Seung KJ, Khan U, Varaine F, Ahmed S, Bastard M, Cloez S, Damtew D, Franke MF, Herboczek K, Huerga H, Islam S, Karakozian H, Khachatryan N, Kliesckova J, Khan AJ, Khan M, Khan P, Kotrikadze T, Lachenal N, Lecca L, Lenggogeni P, Maretbayeva S, Melikyan N, Mesic A, Mitnick CD, Mofolo M, Perrin C, Richard M, Tassew YM, Telnov A, Vilbrun SC, Wanjala S, Rich ML, Hewison C.
Int J Tuberc Lung Dis
View full abstract on Pubmed
Seroprevalence of hepatitis B and hepatitis C among blood donors in Sierra Leone: A multi-year retrospective study.
Authors: Authors: Tognon F, Sevalie S, Gassimu J, Sesay J, Hann K, Sheku M, Bearse E, Di Gennaro F, Marotta C, Pellizzer G, Putoto G, Lado M, Franke MF, Dibba Y, Gevao S, Beynon F, Mesman AW.
Int J Infect Dis
View full abstract on Pubmed