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Alexandra Golby, MD

Professor of Neurosurgery, Harvard Medical School
Professor of Radiology, Harvard Medical School
Department of Global Health and Social Medicine Affiliate
Haley Distinguished Chair in the Neurosciences, Brigham and Women's Hospital
Senior Surgeon, Brigham and Women's Hospital
Director of Image-guided Neurosurgery, Brigham and Women's Hospital
Co-Director AMIGO, Brigham and Women's Hospital

Dr. Golby is a Neurosurgeon and Haley Distinguished Chair in the Neurosciences at Brigham and Women’s Hospital in Boston. She is Professor of Neurosurgery and Professor of Radiology at Harvard Medical School.  She is also Principal Investigator of the Golby Lab, a surgical brain mapping laboratory. Dr. Golby’s clinical focus is on brain surgery for patients with brain tumors and epilepsy, especially those lesions which are intimately associated with critical brain structures. Her translational research is focused on advanced imaging and image guidance to improve care for patients undergoing intracranial neurosurgery. She has developed numerous technologies to help guide presurgical planning and intraoperative decision-making. She works closely with scientists across disciplines including computer science, applied mathematics, MR and ultrasound physics, radiology, neuroscience, and biomedical engineering. She is very involved with mentoring young clinicians and scientists both locally and globally. Dr. Golby was recently a Fulbright Global Scholar pursuing work to foster interdisciplinary collaborations between technical experts and clinicians in host countries Rwanda and Morocco to develop innovative medical technology suited to local conditions.

Dr. Golby received her BA from Yale University and MD from Stanford University School of Medicine. She completed residency training in Neurosurgery at Brigham and Women’s Hospital.

The Golby Lab is a multidisciplinary team of investigators using advanced imaging, image analysis, and computational strategies to develop novel approaches to guide neurosurgery. Areas of interest include using functional MRI to map cortical organization and diffusion MRI to map white matter connections, intra-operative imaging, navigation and guidance, and image guided therapies for brain tumors. She is the co-director of AMIGO, the advanced multi-modality Image guided OR, an NIH-funded translational research operating suite where surgeons and interventionalists work with radiologists and technical experts to develop novel therapies to provide precise, minimally invasive, and effective treatments to patients. She leads the development of NousNav a low-cost open-source neuronavigation system for use in resource-limited settings.

Progestin-associated meningiomatosis with unusual schwannoma-like morphology.
Authors: Authors: Krause KA, Woods JK, Golby AJ, Lee EQ, Tanguturi S, Spigelman Z, Ligon AH, De Girolami U, Torre M.
J Neuropathol Exp Neurol
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Tractography-based automated identification of the retinogeniculate visual pathway with novel microstructure-informed supervised contrastive learning.
Authors: Authors: Li S, Zhang W, Yao S, He J, Zhu C, Gao J, Xue T, Xie G, Chen Y, Torio EF, Feng Y, Bastos DC, Rathi Y, Makris N, Kikinis R, Bi WL, Golby AJ, O'Donnell LJ, Zhang F.
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Transcranial ultrasound neuromodulation for epilepsy: A pilot safety trial.
Authors: Authors: Bubrick EJ, McDannold NJ, Orozco J, Mariano TY, Rigolo L, Golby AJ, Tie Y, White PJ.
Brain Stimul
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Reconstructing the somatotopic organization of the corticospinal tract remains a challenge for modern tractography methods.
Authors: Authors: He J, Zhang F, Pan Y, Feng Y, Rushmore J, Torio E, Rathi Y, Makris N, Kikinis R, Golby AJ, O'Donnell LJ.
Hum Brain Mapp
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SlicerCBM: automatic framework for biomechanical analysis of the brain.
Authors: Authors: Safdar S, Zwick BF, Yu Y, Bourantas GC, Joldes GR, Warfield SK, Hyde DE, Frisken S, Kapur T, Kikinis R, Golby A, Nabavi A, Wittek A, Miller K.
Int J Comput Assist Radiol Surg
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ReMIND: The Brain Resection Multimodal Imaging Database.
Authors: Authors: Juvekar P, Dorent R, Kögl F, Torio E, Barr C, Rigolo L, Galvin C, Jowkar N, Kazi A, Haouchine N, Cheema H, Navab N, Pieper S, Wells WM, Bi WL, Golby A, Frisken S, Kapur T.
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Real-Time Dynamic Data Driven Deformable Registration for Image-Guided Neurosurgery: Computational Aspects.
Authors: Authors: Chrisochoides N, Fedorov A, Liu Y, Kot A, Foteinos P, Drakopoulos F, Tsolakis C, Billias E, Clatz O, Ayache N, Golby A, Black P, Kikinis R.
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Deep Learning for Detection and Localization of B-Lines in Lung Ultrasound.
Authors: Authors: Lucassen RT, Jafari MH, Duggan NM, Jowkar N, Mehrtash A, Fischetti C, Bernier D, Prentice K, Duhaime EP, Jin M, Abolmaesumi P, Heslinga FG, Veta M, Duran-Mendicuti MA, Frisken S, Shyn PB, Golby AJ, Boyer E, Wells WM, Goldsmith AJ, Kapur T.
IEEE J Biomed Health Inform
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Surgical approach to the treatment of pituicytoma. Report of five cases and a literature review.
Authors: Authors: Yasuda ME, Recalde R, Jalón P, Prost D, Golby A, Zaninovich R.
World Neurosurg X
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Glasgow coma scale pupil score (GCS-P) and the hospital mortality in severe traumatic brain injury: analysis of 1,066 Brazilian patients.
Authors: Authors: Bertotti MM, Martins ET, Areas FZ, Vascouto HD, Rangel NB, Melo HM, Lin K, Kupek E, Pizzol FD, Golby AJ, Walz R.
Arq Neuropsiquiatr
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