Leonid Lecca
Leonid Lecca, MD, MSc
Lecturer on Global Health and Social Medicine

Leonid Lecca, MD, MSc is a Lecture in the Department of Global Health and Social Medicine at Harvard Medical School. His research focuses on the epidemiology of tuberculosis, multidrug-resistant tuberculosis, extensively drug-resistant tuberculosis, HIV/AIDS, maternal-health, mental health, chronic diseases and community-based approaches to dealing with public health problems, social responsibility, and public health approaches in global health. Current projects include:

  • The discovery and development of innovative TB Diagnostics.
  • Finding and treating unsuspected and resistant TB to reduce hospital transmission.
  • Identification of metabolic factors that control the spectrum of human tuberculosis.
  • Clinical trials for TB, MDR-TB and XDR-TB.
  • Study of community-based family coaching interventions to improve neurodevelopment in at-risk children.
  • An innovative interdisciplinary approaches to sustainable airborne infection control.
  • Clinical and programmatic outcomes of a community-based antiretroviral therapy program for HIV positive patients.

Dr. Lecca is an international expert on global health. He earned his MD from Cayetano Heredia Peruvian University, where also holds his MSc in Epidemiology and Health Management. Last year, he participated in the Global Health Intensive Program at Harvard T.H. Chan School of Public Health.

Dr. Lecca is also the Executive Director at Partners In Health in Peru, and serve as the principal investigator for numerous NIH and Grand Challenges of Canada grants among others, oversees a staff of 250, manages relationships with government, and facilitates the participation of students and research affiliates on various projects at the PIH site and throughout Peru. In the past, Dr. Lecca worked as a technical advisor in infectious disease projects at U.S. Agency for International Development, and was the Human Research Protection Administrator at the Peruvian National Institute of Health. 

Culture Conversion at 6 Months in Patients Receiving Delamanid-containing Regimens for the Treatment of Multidrug-resistant Tuberculosis.
Authors: Authors: Seung KJ, Khan P, Franke MF, Ahmed S, Aiylchiev S, Alam M, Putri FA, Bastard M, Docteur W, Gottlieb G, Hewison C, Islam S, Khachatryan N, Kotrikadze T, Khan U, Kumsa A, Lecca L, Tassew YM, Melikyan N, Naing YY, Oyewusi L, Rich M, Wanjala S, Yedilbayev A, Huerga H, Mitnick CD.
Clin Infect Dis
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The Use of Wearable Technology to Objectively Measure Sleep Quality and Physical Activity Among Pregnant Women in Urban Lima, Peru: A Pilot Feasibility Study.
Authors: Authors: Galea JT, Ramos K, Coit J, Friedman LE, Contreras C, Dueñas M, Hernandez N, Muster C, Lecca L, Gelaye B.
Matern Child Health J
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Isoniazid Preventive Therapy in Contacts of Multidrug-resistant Tuberculosis.
Authors: Authors: Huang CC, Becerra MC, Calderon R, Contreras C, Galea J, Grandjean L, Lecca L, Yataco R, Zhang Z, Murray M.
Am J Respir Crit Care Med
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A positively selected FBN1 missense variant reduces height in Peruvian individuals.
Authors: Authors: Asgari S, Luo Y, Akbari A, Belbin GM, Li X, Harris DN, Selig M, Bartell E, Calderon R, Slowikowski K, Contreras C, Yataco R, Galea JT, Jimenez J, Coit JM, Farroñay C, Nazarian RM, O'Connor TD, Dietz HC, Hirschhorn JN, Guio H, Lecca L, Kenny EE, Freeman EE, Murray MB, Raychaudhuri S.
Nature
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Peripheral blood mucosal-associated invariant T (MAIT) cells in tuberculosis patients and healthy Mycobacterium tuberculosis-exposed controls.
Authors: Authors: Suliman S, Gela A, Mendelsohn SC, Iwany SK, Tamara KL, Mabwe S, Bilek N, Darboe F, Fisher M, Corbett AJ, Kjer-Nielsen L, Eckle SBG, Huang CC, Zhang Z, Lewinsohn DM, McCluskey J, Rossjohn J, Hatherill M, León SR, Calderon RI, Lecca L, Murray M, Scriba TJ, Van Rhijn I, Moody DB.
J Infect Dis
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Mycobacterium tuberculosis Beijing Lineage and Risk for Tuberculosis in Child Household Contacts, Peru.
Authors: Authors: Huang CC, Chu AL, Becerra MC, Galea JT, Calderón R, Contreras C, Yataco R, Zhang Z, Lecca L, Murray MB.
Emerg Infect Dis
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Severe pulmonary radiological manifestations are associated with a distinct biochemical profile in blood of tuberculosis patients with dysglycemia.
Authors: Authors: Barreda NN, Arriaga MB, Aliaga JG, Lopez K, Sanabria OM, Carmo TA, Fróes Neto JF, Lecca L, Andrade BB, Calderon RI.
BMC Infect Dis
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Two clinical prediction tools to improve tuberculosis contact investigation.
Authors: Authors: Li R, Nordio F, Huang CC, Contreras C, Calderon R, Yataco R, Galea JT, Zhang Z, Becerra MC, Lecca L, Murray MB.
Clin Infect Dis
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CD1b Tetramers Broadly Detect T Cells That Correlate With Mycobacterial Exposure but Not Tuberculosis Disease State.
Authors: Authors: Lopez K, Iwany SK, Suliman S, Reijneveld JF, Ocampo TA, Jimenez J, Calderon R, Lecca L, Murray MB, Moody DB, Van Rhijn I.
Front Immunol
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A TCR ß-Chain Motif Biases toward Recognition of Human CD1 Proteins.
Authors: Authors: Reinink P, Shahine A, Gras S, Cheng TY, Farquhar R, Lopez K, Suliman SA, Reijneveld JF, Le Nours J, Tan LL, León SR, Jimenez J, Calderon R, Lecca L, Murray MB, Rossjohn J, Moody DB, Van Rhijn I.
J Immunol
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