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Maha Reda Farhat, MD
Instructor in Medicine and Department of Global Health and Social Medicine Affiliate

Maha Farhat  holds an MD from the McGill University Faculty of Medicine and a MSc in biostatistics from the Harvard Chan School of Public Health. She is also a practicing physician at the Massachusetts General Hospital Division of Pulmonary and Critical Care Medicine.

Program in Global Surgery and Social Change


    Dr. Farhat's research focuses on the development and application of methods for associating genotype and phenotype in infectious disease pathogens, with a strong emphasis on translation to better diagnostics and surveillance in resource-poor settings. To date, Farhat's work has focused on the pathogen Mycobacterium tuberculosis and spans the spectrum from computational analysis to field studies. She is PI and Co-Investigator on several large projects funded by NIH including the NIAID and the BD2K initiative.

    DBMI Research Areas
    DBMI Courses



    Tuberculosis Pathways to Care and Transmission of Multidrug Resistance in India.
    Authors: Authors: Atre SR, Jagtap JD, Faqih MI, Dumbare YK, Sawant TU, Ambike SL, Bhawalkar JS, Bharaswadkar SK, Jogewar PK, Adkekar RS, Hodgar BP, Jadhav V, Mokashi ND, Golub JE, Dixit A, Farhat MR.
    Am J Respir Crit Care Med
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    Benchmarking the empirical accuracy of short-read sequencing across the M. tuberculosis genome.
    Authors: Authors: Marin M, Vargas R, Harris M, Jeffrey B, Epperson LE, Durbin D, Strong M, Salfinger M, Iqbal Z, Akhundova I, Vashakidze S, Crudu V, Rosenthal A, Farhat MR.
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    Whole Genome Sequencing Assessing Impact of Diabetes Mellitus on Tuberculosis Mutations and Type of Recurrence in India.
    Authors: Authors: Mave V, Chen L, Ranganathan UD, Kadam D, Vishwanathan V, Lokhande R, S SK, Kagal A, Pradhan NN, Shivakumar SVBY, S Paradkar M, Deshmukh S, Tornheim JA, Kornfeld H, Farhat M, Gupta A, Padmapriyadarsini C, Gupte N, Golub JE, Mathema B, Kreiswirth BN.
    Clin Infect Dis
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    Fecal microbiota transplantation and Clostridioides difficile infection among privately insured patients in the United States.
    Authors: Authors: El Halabi J, Palmer N, Fox K, Kohane I, Farhat MR.
    J Gastroenterol
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    Population structure, biogeography and transmissibility of Mycobacterium tuberculosis.
    Authors: Authors: Freschi L, Vargas R, Husain A, Kamal SMM, Skrahina A, Tahseen S, Ismail N, Barbova A, Niemann S, Cirillo DM, Dean AS, Zignol M, Farhat MR.
    Nat Commun
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    Role of Epistasis in Amikacin, Kanamycin, Bedaquiline, and Clofazimine Resistance in Mycobacterium tuberculosis Complex.
    Authors: Authors: Vargas R, Freschi L, Spitaleri A, Tahseen S, Barilar I, Niemann S, Miotto P, Cirillo DM, Köser CU, Farhat MR.
    Antimicrob Agents Chemother
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    Association Between NEDD4L Variation and the Genetic Risk of Acute Appendicitis: A Multi-institutional Genome-Wide Association Study.
    Authors: Authors: Gaitanidis A, Kaafarani HMA, Christensen MA, Breen K, Mendoza A, Fagenholz PJ, Velmahos GC, Farhat MR.
    JAMA Surg
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    GenTB: A user-friendly genome-based predictor for tuberculosis resistance powered by machine learning.
    Authors: Authors: Gröschel MI, Owens M, Freschi L, Vargas R, Marin MG, Phelan J, Iqbal Z, Dixit A, Farhat MR.
    Genome Med
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    Diagnostic deficiencies of C. difficile infection among patients in a tertiary hospital in Saudi Arabia: A laboratory-based case series.
    Authors: Authors: AlJindan R, AlEraky DM, Borgio JF, AbdulAzeez S, Abdalhamid B, Mahmoud N, Farhat M.
    Saudi J Biol Sci
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    Measuring health-care delays among privately insured patients with tuberculosis in the USA: an observational cohort study.
    Authors: Authors: El Halabi J, Palmer N, McDuffie M, Golub JJ, Fox K, Kohane I, Farhat MR.
    Lancet Infect Dis
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