Maha Farhat holds an MD from the McGill University Faculty of Medicine and a MSc in biostatistics from the Harvard Chan School of Public Health. She is also a practicing physician at the Massachusetts General Hospital Division of Pulmonary and Critical Care Medicine.
Dr. Farhat's research focuses on the development and application of methods for associating genotype and phenotype in infectious disease pathogens, with a strong emphasis on translation to better diagnostics and surveillance in resource-poor settings. To date, Farhat's work has focused on the pathogen Mycobacterium tuberculosis and spans the spectrum from computational analysis to field studies. She is PI and Co-Investigator on several large projects funded by NIH including the NIAID and the BD2K initiative.
DBMI Research Areas
DBMI Courses
Complete genome sequence of a virulent barcoded Mycobacterium tuberculosis str. Erdman commonly used for non-human primate infection studies.
Authors: Authors: Marin MG, Chase MR, Quinones N, Wakabayashi S, Mugahid D, Fortune SM, Farhat MR, Chao MC.
Microbiol Resour Announc
View full abstract on Pubmed
Microbiol Resour Announc
View full abstract on Pubmed
Patient Determinants and Effects on Adherence of Adverse Drug Reactions to Tuberculosis Treatment: A Prospective Cohort Analysis.
Authors: Authors: Tzelios CA, Malatesta S, Carney T, White LF, Weber SE, Thomson S, Theron D, Myers B, Parry CDH, Warren RM, Horsburgh CR, Farhat MR, Jacobson KR.
Clin Infect Dis
View full abstract on Pubmed
Clin Infect Dis
View full abstract on Pubmed
Frequently arising ESX-1-associated phase variants influence Mycobacterium tuberculosis fitness in the presence of host and antibiotic pressures.
Authors: Authors: Luna MJ, Oluoch PO, Miao J, Culviner P, Papavinasasundaram K, Jaecklein E, Shell SS, Ioerger TR, Fortune SM, Farhat MR, Sassetti CM.
mBio
View full abstract on Pubmed
mBio
View full abstract on Pubmed
Phyla: Towards a foundation model for phylogenetic inference.
Authors: Authors: Shen A, Ektefaie Y, Jain L, Farhat M, Zitnik M.
bioRxiv
View full abstract on Pubmed
bioRxiv
View full abstract on Pubmed
Precision phenotyping for curating research cohorts of patients with unexplained post-acute sequelae of COVID-19.
Authors: Authors: Azhir A, Hügel J, Tian J, Cheng J, Bassett IV, Bell DS, Bernstam EV, Farhat MR, Henderson DW, Lau ES, Morris M, Semenov YR, Triant VA, Visweswaran S, Strasser ZH, Klann JG, Murphy SN, Estiri H.
Med
View full abstract on Pubmed
Med
View full abstract on Pubmed
A Genome-wide Association Study Reveals a Novel Susceptibility Locus for Pancreas Divisum at 3q29.
Authors: Authors: Gaitanidis A, Christensen MA, Breen KA, Kambadakone AR, Joshipura ND, Fernandez-Del Castillo C, Hernandez-Barco YG, Kaafarani HMA, Velmahos GC, Farhat MR, Fagenholz PJ.
J Surg Res
View full abstract on Pubmed
J Surg Res
View full abstract on Pubmed
Erratum for Poonawala et al., "Transcriptomic responses to antibiotic exposure in Mycobacterium tuberculosis".
Authors: Authors: Poonawala H, Zhang Y, Kuchibhotla S, Green AG, Cirillo DM, Di Marco F, Spitaleri A, Miotto P, Farhat MR.
Antimicrob Agents Chemother
View full abstract on Pubmed
Antimicrob Agents Chemother
View full abstract on Pubmed
Percent of lung involved in disease on chest X-ray predicts unfavorable treatment outcome in pulmonary tuberculosis.
Authors: Authors: Ghanem M, Srivastava R, Ektefaie Y, Hoppes D, Rosenfeld G, Yaniv Z, Grinev A, Xu AY, Yang E, Velásquez GE, Harrison L, Rosenthal A, Savic RM, Jacobson KR, Farhat MR.
medRxiv
View full abstract on Pubmed
medRxiv
View full abstract on Pubmed
Differential rates of Mycobacterium tuberculosis transmission associate with host-pathogen sympatry.
Authors: Authors: Gröschel MI, Pérez-Llanos FJ, Diel R, Vargas R, Escuyer V, Musser K, Trieu L, Meissner JS, Knorr J, Klinkenberg D, Kouw P, Homolka S, Samek W, Mathema B, van Soolingen D, Niemann S, Ahuja SD, Farhat MR.
Nat Microbiol
View full abstract on Pubmed
Nat Microbiol
View full abstract on Pubmed
Beyond diagnostic connectivity: Leveraging digital health technology for the real-time collection and provision of high-quality actionable data on infectious diseases in Uganda.
Authors: Authors: Mujuni D, Tumwine J, Musisi K, Otim E, Farhat MR, Nabulobi D, Abdunoor N, Tumuhairwe AK, Mugisa MD, Oola D, Semitala F, Byaruhanga R, Turyahabwe S, Joloba M.
PLOS Digit Health
View full abstract on Pubmed
PLOS Digit Health
View full abstract on Pubmed