Image of Maha Reda Farhat

Maha Reda Farhat, M.D., M.D.,C.M.

617-432-4598

Maha Farhat  holds an MD from the McGill University Faculty of Medicine and a MSc in biostatistics from the Harvard Chan School of Public Health. She is also a practicing physician at the Massachusetts General Hospital Division of Pulmonary and Critical Care Medicine.

Program in Global Surgery and Social Change

Dr. Farhat's research focuses on the development and application of methods for associating genotype and phenotype in infectious disease pathogens, with a strong emphasis on translation to better diagnostics and surveillance in resource-poor settings. To date, Farhat's work has focused on the pathogen Mycobacterium tuberculosis and spans the spectrum from computational analysis to field studies. She is PI and Co-Investigator on several large projects funded by NIH including the NIAID and the BD2K initiative.


DBMI Research Areas
DBMI Courses
Phase variation as a major mechanism of adaptation in Mycobacterium tuberculosis complex.
Authors: Authors: Vargas R, Luna MJ, Freschi L, Marin M, Froom R, Murphy KC, Campbell EA, Ioerger TR, Sassetti CM, Farhat MR.
Proc Natl Acad Sci U S A
View full abstract on Pubmed
Analysis of Genome-Wide Mutational Dependence in Naturally Evolving Mycobacterium tuberculosis Populations.
Authors: Authors: Green AG, Vargas R, Marin MG, Freschi L, Xie J, Farhat MR.
Mol Biol Evol
View full abstract on Pubmed
Mutation rates and adaptive variation among the clinically dominant clusters of Mycobacterium abscessus.
Authors: Authors: Commins N, Sullivan MR, McGowen K, Koch EM, Rubin EJ, Farhat M.
Proc Natl Acad Sci U S A
View full abstract on Pubmed
High-throughput phenogenotyping of Mycobacteria tuberculosis clinical strains reveals bacterial determinants of treatment outcomes.
Authors: Authors: Stanley S, Spaulding CN, Liu Q, Chase MR, Ha DTM, Thai PVK, Lan NH, Thu DDA, Quang NL, Brown J, Hicks ND, Wang X, Marin M, Howard NC, Vickers AJ, Karpinski WM, Chao MC, Farhat MR, Caws M, Dunstan SJ, Thuong NTT, Fortune SM.
bioRxiv
View full abstract on Pubmed
Clinical implications of molecular drug resistance testing for Mycobacterium tuberculosis: a 2023 TBnet/RESIST-TB consensus statement.
Authors: Authors: Domínguez J, Boeree MJ, Cambau E, Chesov D, Conradie F, Cox V, Dheda K, Dudnyk A, Farhat MR, Gagneux S, Grobusch MP, Gröschel MI, Guglielmetti L, Kontsevaya I, Lange B, van Leth F, Lienhardt C, Mandalakas AM, Maurer FP, Merker M, Miotto P, Molina-Moya B, Morel F, Niemann S, Veziris N, Whitelaw A, Horsburgh CR, Lange C.
Lancet Infect Dis
View full abstract on Pubmed
Multimodal learning with graphs.
Authors: Authors: Ektefaie Y, Dasoulas G, Noori A, Farhat M, Zitnik M.
Nat Mach Intell
View full abstract on Pubmed
Optimizing DNA Extraction from Pediatric Stool for Diagnosis of Tuberculosis and Use in Next-Generation Sequencing Applications.
Authors: Authors: Ness TE, Meiwes L, Kay A, Mejia R, Lange C, Farhat M, Mandalakas A, DiNardo A.
Microbiol Spectr
View full abstract on Pubmed
COVID-19 bacteremic co-infection is a major risk factor for mortality, ICU admission, and mechanical ventilation.
Authors: Authors: Patton MJ, Orihuela CJ, Harrod KS, Bhuiyan MAN, Dominic P, Kevil CG, Fort D, Liu VX, Farhat M, Koff JL, Lal CV, Gaggar A, Richter RP, Erdmann N, Might M, Gaggar A.
Crit Care
View full abstract on Pubmed
Rethinking global digital health and AI-for-health innovation challenges.
Authors: Authors: Farlow A, Hoffmann A, Tadesse GA, Mzurikwao D, Beyer R, Akogo D, Weicken E, Matika T, Nweje MI, Wamae W, Arts S, Wiegand T, Bennett C, Farhat MR, Gröschel MI.
PLOS Glob Public Health
View full abstract on Pubmed
Addressing patients' unmet needs related to multidrug-resistant tuberculosis (MDR-TB) care: A qualitative research study from Pune city, India.
Authors: Authors: Atre S, Jagtap J, Faqih M, Dumbare Y, Sawant T, Ambike S, Farhat M.
PLoS One
View full abstract on Pubmed